Rapid Electrochemical Monitoring of Tyrosine by Poly (Riboflavin) Modified Carbon Nanotube Paste Electrode as a Sensitive Sensor and its Applications in Pharmaceutical Samples

被引:4
|
作者
D'Souza, Edwin Santhan [1 ,2 ]
Manjunatha, Jamballi G. [1 ]
Chenthattil, Raril [1 ]
Tigari, Girish [1 ]
Ravishankar, Doddarasinakere K. [3 ]
机构
[1] Mangalore Univ, FMKMC Coll, Dept Chem, Constituent Coll, Madikeri, Karnataka, India
[2] St Philomena Coll, Dept Chem, Puttur, Karnataka, India
[3] Sri Mahadeshwara Govt First Grade Coll, Dept Chem, Chamarajanagar, Karnataka, India
来源
关键词
Poly(riboflavin); tyrosine; electrochemical sensor; carbon nanotube paste electrode; voltammetry; PERFORMANCE LIQUID-CHROMATOGRAPHY; ASCORBIC-ACID; VOLTAMMETRIC DETERMINATION; AMINO-ACIDS; SPECTROPHOTOMETRIC DETERMINATION; SELECTIVE DETERMINATION; SILVER NANOPARTICLES; STAINLESS-STEEL; GRAPHENE OXIDE; L-TRYPTOPHAN;
D O I
10.33263/BRIAC116.1466114672
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A poly(riboflavin) modified carbon nanotube paste electrode (PRFMCNTPE) is employed as a compatible and electrocatalytic sensor for the determination of Tyrosine (TYR). The analysis and assessment are carried out through differential pulse voltammetry (DPV) and Cyclic Voltammetry (CV). The surface of the intended sensor is examined through Field Emission Scanning Electron Microscopy (FE-SEM). The modified electrode shows the outstanding electrocatalytic effect for TYR with high selectivity and sensitivity as compared to carbon nanotube paste electrode (CNTPE). The electro-oxidation peak current of TYR and its concentration is found linear from 2 mu M to 10 mu M with a detection limit (LOD) of 0.45 mu M. The developed sensor is productively applied for the determination of TYR in pharmaceutical samples like Tyrosine capsules. The adapted electrode shows good stability, excellent reproducibility, and remarkable sensitivity.
引用
收藏
页码:14661 / 14672
页数:12
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