Combinatorial Targeting of Leukemia and Stromal Cells Overcomes Fms-like Tyrosine Kinase 3 (FLT3) Inhibitor Resistance in Acute Myeloid Leukemia (AML)

被引:0
|
作者
Bhattacharya, Seemana [1 ,2 ]
Mu, Hong [1 ,2 ]
Piya, Sujan [1 ,2 ]
Zhang, Weiguo [1 ,2 ]
McQueen, Teresa [1 ,2 ]
Paradiso, Linda [3 ]
Oberkovitz, Galia [4 ]
Benami, Eyal [4 ]
Andreeff, Michael [1 ,2 ]
Borthakur, Gautam [1 ,2 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Sect Mol Hematol & Therapy, Houston, TX 77030 USA
[3] Strategia Therapeut Inc, 28420 Hardy Toll Rd,Suite 110, Spring, TX USA
[4] BioLineRx Ltd, Modiin Technol Pk 2,HaMaayan St, Modiin, Israel
来源
关键词
AML; FLT3-ITD; dual MEK1-FLT3 inhibitor; peptidic CXCR4-antagonist; leukemia-stroma interactions;
D O I
10.1016/j.clml.2017.07.049
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
AML-033
引用
收藏
页码:S273 / S273
页数:1
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