BrainProfileDB - a platform for integration of functional genomics data

被引:7
|
作者
Schuchhardt, Johannes [1 ]
Glintschert, Alexander [1 ]
Hartl, Daniela [2 ]
Irmler, Martin [3 ]
Beckers, Johannes [3 ,4 ]
Stephan, Christian [5 ]
Marcus, Katrin [5 ]
Klose, Joachim [2 ]
Meyer, Helmut E. [5 ]
Malik, Arif [1 ]
机构
[1] Microdiscovery GmbH, D-10405 Berlin, Germany
[2] Charite, Inst Human Genet, D-13353 Berlin, Germany
[3] German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Expt Genet, Neuherberg, Germany
[4] Tech Univ Munich, Ctr Life & Food Sci Weihenstephan, Chair Expt Genet, Weihenstephan, Germany
[5] Ruhr Univ Bochum, Med Proteom Ctr, Bochum, Germany
关键词
data analysis; functional genomics database; high-throughput data management; integrating genomics and proteomics; neurodegenerative diseases;
D O I
10.1002/pmic.200700743
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
BrainProfileDB is a database system for integrating large sets of high throughput functional genomics data of the Human Brain Proteome Project (HBPP). Within HBPP (http://www.smp.proteomics.de/) the molecular pathology of neurodegenerative diseases is investigated, using complementary methods from transcriptomics, proteomics, toponomics and interaction measurements. Aim of the database system is to provide a broad spectrum of scientific users joined in the consortium with a practical integrated view on their data. Employing appropriate mapping techniques and levels of data representation the user is relieved from technical details of gene identification or experimental measurement technique.
引用
收藏
页码:1162 / 1164
页数:3
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