Effects of Heparin on Synaptic Activity in the Hemorrhagic Stroke Model

被引：2

作者：

Mokrushin, A. A. ^{[1
]}

Pavlinova, L. I. ^{[1
]}

机构：

[1] Russian Acad Sci, IP Pavlov Physiol Inst, St Petersburg 196140, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2012年 / 152卷 / 06期

关键词：

surviving slices; hemorrhagic stroke; focal potentials; heparin; GROWTH-ASSOCIATED MOLECULE; HB-GAM; SULFATE; MATURATION; AGRIN;

D O I：

10.1007/s10517-012-1606-y

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We studied the ability of heparin to modify synaptic activity on the original stroke model . Cultured slices of the brain slices from hypertensive rats were treated with the auto blood clot. Administration of heparin (2 mg/ml) before autoblood treatment had a protective effect on ionotropic glutamatergic and GABAergic receptors, whose activity was inhibited by the blood.

引用

页码：684 / 687

页数：4

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