The relationship between regulatory T cells and radiation therapy

被引：3
|
作者：
Hou, P-F [1 ]
Zhua, L-J [1 ]
Pan, Y. [1 ]
Sun, X-C [2 ]
Pu, J. [3 ]
机构：
[1] Lianshui Cty Peoples Hosp, Dept Clin Lab, Lianshui, Peoples R China
[2] Nanjing Med Univ, Affiliated Hosp 1, Dept Radiat Oncol, Nanjing, Peoples R China
[3] Lianshui Cty Peoples Hosp, Dept Radiat Oncol, Lianshui, Peoples R China
来源：
CANCER RADIOTHERAPIE | 2020年 / 24卷 / 01期
关键词：
Tregs; Radiotherapy; Cancer; Relationship; SERUM CARCINOEMBRYONIC ANTIGEN; CYFRA; 21-1; RADIOTHERAPY; SURVIVAL; METASTASIS; MECHANISMS; GAMMA;
D O I：
10.1016/j.canrad.2019.07.160
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Radiation therapy (RT) is an effective treatment for cancer. Approximately, 70% of cancer patients receive RT in China. The immune-modulating effect of radiation therapy have gained considerable interest in recent years and there have been multiple reports of synergy between radiation and immunotherapy. Regulatory T cells (Tregs) are a group of T cell subsets with immunosuppressive function, which is correlated with cancer. Tregs are involved in the pathogenesis, development, treatment and prognosis of tumors by cell-cell contact, cytokines, and cell metabolism. Based on the immunological characteristics of Tregs, this article reviews the interaction between RT and immune molecules, aiming to provide new ideas for RT combined with immunotherapy. (C) 2020 Societe francaise de radiotherapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：81 / 84
页数：4
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