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Benefits of Pulmonary Rehabilitation in Idiopathic Pulmonary Fibrosis
被引:78
|作者:
Swigris, Jeffrey J.
[1
,2
]
Fairclough, Diane L.
[3
]
Morrison, Marianne
[1
,2
]
Make, Barry
[4
]
Kozora, Elizabeth
[5
]
Brown, Kevin K.
[1
,2
]
Wamboldt, Frederick S.
[5
]
机构:
[1] Natl Jewish Hlth, Autoimmune Lung Ctr, Denver, CO 80206 USA
[2] Natl Jewish Hlth, Interstitial Lung Dis Program, Denver, CO 80206 USA
[3] Univ Colorado, Colorado Hlth Outcomes Program, Denver, CO 80202 USA
[4] Univ Colorado, COPD Program, Denver, CO 80202 USA
[5] Univ Colorado, Div Psychosocial Med, Denver, CO 80202 USA
基金:
美国国家卫生研究院;
关键词:
pulmonary rehabilitation;
idiopathic pulmonary fibrosis;
IPF;
outcomes;
functional capacity;
fatigue;
QUALITY-OF-LIFE;
VOLUME-REDUCTION SURGERY;
6-MIN WALK TEST;
SLEEP QUALITY;
VALUES;
D O I:
10.4187/respcare.00939
中图分类号:
R4 [临床医学];
学科分类号:
1002 ;
100602 ;
摘要:
BACKGROUND: Information on the benefits of pulmonary rehabilitation (PR) in patients with idiopathic pulmonary fibrosis (IPF) is growing, but PR's effects on certain important outcomes is lacking. METHODS: We conducted a pilot study of PR in IPF and analyzed changes in functional capacity, fatigue, anxiety, depression, sleep, and health status from baseline to after completion of a standard, 6-week PR program. RESULTS: Six-min walk distance improved a mean +/- standard error 202 +/- 135 feet (P = .01) from baseline. Fatigue Severity Scale score also improved significantly, declining an average 1.5 +/- 0.5 points from baseline. There were trends toward improvement in anxiety, depression, and health status. CONCLUSIONS: PR improves functional capacity and fatigue in patients with IPF. (ClinicalTrials.gov registration NCT00692796.)
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页码:783 / 789
页数:7
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