Benefits of Pulmonary Rehabilitation in Idiopathic Pulmonary Fibrosis

被引:78
|
作者
Swigris, Jeffrey J. [1 ,2 ]
Fairclough, Diane L. [3 ]
Morrison, Marianne [1 ,2 ]
Make, Barry [4 ]
Kozora, Elizabeth [5 ]
Brown, Kevin K. [1 ,2 ]
Wamboldt, Frederick S. [5 ]
机构
[1] Natl Jewish Hlth, Autoimmune Lung Ctr, Denver, CO 80206 USA
[2] Natl Jewish Hlth, Interstitial Lung Dis Program, Denver, CO 80206 USA
[3] Univ Colorado, Colorado Hlth Outcomes Program, Denver, CO 80202 USA
[4] Univ Colorado, COPD Program, Denver, CO 80202 USA
[5] Univ Colorado, Div Psychosocial Med, Denver, CO 80202 USA
基金
美国国家卫生研究院;
关键词
pulmonary rehabilitation; idiopathic pulmonary fibrosis; IPF; outcomes; functional capacity; fatigue; QUALITY-OF-LIFE; VOLUME-REDUCTION SURGERY; 6-MIN WALK TEST; SLEEP QUALITY; VALUES;
D O I
10.4187/respcare.00939
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
BACKGROUND: Information on the benefits of pulmonary rehabilitation (PR) in patients with idiopathic pulmonary fibrosis (IPF) is growing, but PR's effects on certain important outcomes is lacking. METHODS: We conducted a pilot study of PR in IPF and analyzed changes in functional capacity, fatigue, anxiety, depression, sleep, and health status from baseline to after completion of a standard, 6-week PR program. RESULTS: Six-min walk distance improved a mean +/- standard error 202 +/- 135 feet (P = .01) from baseline. Fatigue Severity Scale score also improved significantly, declining an average 1.5 +/- 0.5 points from baseline. There were trends toward improvement in anxiety, depression, and health status. CONCLUSIONS: PR improves functional capacity and fatigue in patients with IPF. (ClinicalTrials.gov registration NCT00692796.)
引用
收藏
页码:783 / 789
页数:7
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