Comparison of effects of vitamin C and selenium on renal and hepatic superoxide dismutase activities in cadmium intoxicated rats

被引：0

作者：

Domanska, K ^{[1
]}

Grosicki, A

机构：

[1] Natl Inst Vet Res, Dept Poultry Dis, PL-24100 Pulawy, Poland

[2] Natl Inst Vet Res, Lab Radiol Protect & Isotop Res, PL-24100 Pulawy, Poland

来源：

BULLETIN OF THE VETERINARY INSTITUTE IN PULAWY | 2000年 / 44卷 / 02期

关键词：

superoxide dismutase; vitamin C; selenium; cadmium chloride; rats;

D O I：

暂无

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Male Wistar rats on a standard or vitamin C or selenium supplemented diet received orally a solution of cadmium chloride at a dose corresponding to 10 mg of cadmium/kg of diet. Rats were killed within 28 days of cadmium administration. Results showed that the cadmium intoxication decreased renal and hepatic superoxide dismutase (SOD) activity on day 7 and increased on days 14, 21 and 28. Rats fed the selenium or vitamin C supplemented diet exhibited time- and organ-dependent alterations in SOD activity. In several time-points results varied from those found in intact rats and those treated with cadmium.

引用

页码：247 / 251

页数：5

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