Comparison of effects of vitamin C and selenium on renal and hepatic superoxide dismutase activities in cadmium intoxicated rats

被引：0
|
作者：
Domanska, K [1 ]
Grosicki, A
机构：
[1] Natl Inst Vet Res, Dept Poultry Dis, PL-24100 Pulawy, Poland
[2] Natl Inst Vet Res, Lab Radiol Protect & Isotop Res, PL-24100 Pulawy, Poland
来源：
BULLETIN OF THE VETERINARY INSTITUTE IN PULAWY | 2000年 / 44卷 / 02期
关键词：
superoxide dismutase; vitamin C; selenium; cadmium chloride; rats;
D O I：
暂无
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Male Wistar rats on a standard or vitamin C or selenium supplemented diet received orally a solution of cadmium chloride at a dose corresponding to 10 mg of cadmium/kg of diet. Rats were killed within 28 days of cadmium administration. Results showed that the cadmium intoxication decreased renal and hepatic superoxide dismutase (SOD) activity on day 7 and increased on days 14, 21 and 28. Rats fed the selenium or vitamin C supplemented diet exhibited time- and organ-dependent alterations in SOD activity. In several time-points results varied from those found in intact rats and those treated with cadmium.
引用
收藏
页码：247 / 251
页数：5
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