Enantio- and Diastereoselective Synthesis of syn-β-Hydroxyallylsilanes via a Chiral (Z)-γ-Silylailylboronate

被引：27

作者：

Lira, Ricardo ^{[1
]}

Roush, William R. ^{[1
]}

机构：

[1] Scripps Florida, Dept Chem, Jupiter, FL 33458 USA

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 21期

关键词：

D O I：

10.1021/ol7018746

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

syn-beta-Hydroxyallylsilanes of general structure 11 and 28 are prepared in 50-86% yield and 91-95% ee (for aliphatic aldehydes; 50% ee for benzaldehyde) via the BF(3)center dot Et(2)O-promoted gamma-silylallylboration reactions, using reagents 14 and 15.

引用

页码：4315 / 4318

页数：4

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