Synthesis, Structure, and Antiproliferative Activity of Three Gallium(III) Azole Complexes

被引：22

作者：

Zanias, Stergios ^{[2
]}

Papaefstathiou, Giannis S. ^{[3
]}

Raptopoulou, Catherine P. ^{[4
]}

Papazisis, Konstantinos T. ^{[5
]}

Vala, Vasiliki ^{[5
]}

Zambouli, Dimitra ^{[5
]}

Kortsaris, Alexandros H. ^{[5
]}

Kyriakidis, Dimitrios A. ^{[1
,6
]}

Zafiropoulos, Theodoros F. ^{[2
]}

机构：

[1] Aristotle Univ Thessaloniki, Dept Chem, Thessaloniki 54124, Greece

[2] Univ Patras, Dept Chem, Patras 26504, Greece

[3] Natl & Kapodistrian Univ Athens, Dept Chem, Inorgan Chem Lab, Panepistimiopolis 15771, Zografou, Greece

[4] NCSR Demokritos, Inst Mat Sci, Aghia Paraskevi 15310, Greece

[5] Theagenion Krankenhauses, Thessaloniki 54007, Greece

[6] Natl Hellen Res Fdn, Athens 11635, Greece

来源：

BIOINORGANIC CHEMISTRY AND APPLICATIONS | 2010年 / 2010卷

关键词：

CRYSTAL-STRUCTURE; CELL-LINE; IN-VITRO; ANTITUMOR; CHEMISTRY; BINDING; LIGAND;

D O I：

10.1155/2010/168030

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

As part of our interest into the bioinorganic chemistry of gallium, gallium(III) complexes of the azole ligands 2,1,3-benzothiadiazole (btd), 1,2,3-benzotriazole (btaH), and 1-methyl-4,5-diphenylimidazole (L) have been isolated. Reaction of btaH or btd with GaBr3 or GaCl3 resulted in the mononuclear complexes [ GaBr3(btaH) 2] (1) and [ GaCl3(btd) 2] (2), respectively, while treatment of GaCl3 with L resulted in the anionic complex (LH)(2)[GaCl4] (3). All three complexes were characterized by single-crystal X-ray crystallography and IR spectroscopy, while their antiproliferative activities were investigated against a series of human and mouse cancer cell lines.

引用

页数：10

共 50 条

[21] Synthesis and structures of (porphinato)(thiolato)gallium(III) complexes
Okamura, T
Nishikawa, N
Ueyama, N
Nakamura, A
CHEMISTRY LETTERS, 1998, (03) : 199 - 200
[22] Synthesis and characterization of phosphinic and phosphate complexes of gallium(III) and indium(III)
Dutta, DP
Jain, VK
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2000, 166 : 15 - 26
[23] Synthesis and Structural Studies of Gallium(III) and Iron(III) Hemicryptophane Complexes
Gosse, Isabelle
Robeyns, Koen
Bougault, Catherine
Martinez, Alexandre
Tinant, Bernard
Dutasta, Jean-Pierre
INORGANIC CHEMISTRY, 2016, 55 (03) : 1011 - 1013
[24] Synthesis, Crystal Structure and Catalytic Activity Palladium(II) Complexes Containing Bulky Azole Ligands
Zhang Meng-Yao
Zhang Ying-Ying
Zhang Hui-Xin
Wang Shen
Wang Ya-Qi
Zeng Yong-Fei
Liu Gui-Yan
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2020, 39 (09) : 1669 - 1674
[25] Synthesis, structure and antiproliferative activity of dinuclear ruthenium arene complexes with differently coordinated thiosemicarbazones
Su, Wei
Li, Yuchun
Xiao, Jun-an
Zhang, Yuexing
Li, Peiyuan
APPLIED ORGANOMETALLIC CHEMISTRY, 2018, 32 (08)
[26] Ruthenium(II) arene complexes containing benzhydrazone ligands: synthesis, structure and antiproliferative activity
Subarkhan, Mohamed Kasim Mohamed
Ramesh, Rengan
INORGANIC CHEMISTRY FRONTIERS, 2016, 3 (10): : 1245 - 1255
[27] Striking Difference in Antiproliferative Activity of Ruthenium- and Osmium-Nitrosyl Complexes with Azole Heterocycles
Buechel, Gabriel E.
Gavriluta, Anatolie
Novak, Maria
Meier, Samuel M.
Jakupec, Michael A.
Cuzan, Olesea
Turta, Constantin
Tommasino, Jean-Bernard
Jeanneau, Erwann
Novitchi, Ghenadie
Luneau, Dominique
Arion, Vladimir B.
INORGANIC CHEMISTRY, 2013, 52 (11) : 6273 - 6285
[28] Gallium(III)- and Thallium(III)-Encapsulated Polyoxopalladates: Synthesis, Structure, Multinuclear NMR, and Biological Activity Studies
Ma, Tian
Ma, Xiang
Lin, Zhengguo
Zhang, Jiayao
Yang, Peng
Csupasz, Tibor
Toth, Imre
Misirlic-Dencic, Sonja
Isakovic, Andjelka M.
Lembo, David
Donalisio, Manuela
Kortz, Ulrich
INORGANIC CHEMISTRY, 2023, 62 (33) : 13195 - 13204
[29] Structure-activity relationship of antitumour ruthenium azole complexes
Arion, V
Eichinger, A
Jakupec, M
Keppler, BK
JOURNAL OF INORGANIC BIOCHEMISTRY, 2001, 86 (01) : 129 - 129
[30] Antiproliferative Pt(IV) complexes: synthesis, biological activity, and quantitative structure-activity relationship modeling
Gramatica, Paola
Papa, Ester
Luini, Mara
Monti, Elena
Gariboldi, Marzia B.
Ravera, Mauro
Gabano, Elisabetta
Gaviglio, Luca
Osella, Domenico
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2010, 15 (07): : 1157 - 1169

← 1 2 3 4 5 →