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BEAMing Sheds Light on Drug Resistance
被引:3
|作者:
Lauring, Josh
[1
]
Park, Ben Ho
[1
]
机构:
[1] Johns Hopkins, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD 21287 USA
关键词:
LUNG-CANCER;
MUTATION;
T790M;
EGFR;
DNA;
D O I:
10.1158/1078-0432.CCR-11-2556
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Targeted therapies against somatically altered genes are currently used for the treatment of many human cancers. The nascent technology known as BEAMing has the potential to increase the clinical utility of these agents because it allows for the detection of cancer mutations in peripheral blood, providing a rapid assessment of tumor mutation status. Clin Cancer Res; 17(24); 7508-10. (C)2011 AACR.
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页码:7508 / 7510
页数:3
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