BEAMing Sheds Light on Drug Resistance

被引:3
|
作者
Lauring, Josh [1 ]
Park, Ben Ho [1 ]
机构
[1] Johns Hopkins, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD 21287 USA
关键词
LUNG-CANCER; MUTATION; T790M; EGFR; DNA;
D O I
10.1158/1078-0432.CCR-11-2556
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Targeted therapies against somatically altered genes are currently used for the treatment of many human cancers. The nascent technology known as BEAMing has the potential to increase the clinical utility of these agents because it allows for the detection of cancer mutations in peripheral blood, providing a rapid assessment of tumor mutation status. Clin Cancer Res; 17(24); 7508-10. (C)2011 AACR.
引用
收藏
页码:7508 / 7510
页数:3
相关论文
共 50 条
  • [33] Structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase-dihydropteroate synthase from Plasmodium vivax sheds light on drug resistance
    Yogavel, Manickam
    Nettleship, Joanne E.
    Sharma, Akansha
    Harlos, Karl
    Jamwal, Abhishek
    Chaturvedi, Rini
    Sharma, Manmohan
    Jain, Vitul
    Chhibber-Goel, Jyoti
    Sharma, Amit
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 293 (39) : 14962 - 14972
  • [34] Beaming Visible Light with a Plasmonic Aperture Antenna
    Yi, Jue-Min
    Cuche, Aurelien
    Devaux, Eloise
    Genet, Cyriaque
    Ebbesen, Thomas W.
    ACS PHOTONICS, 2014, 1 (04): : 365 - 370
  • [35] Adaptable light beaming and shaping with lens array
    1600, Blackwell Publishing Ltd (45):
  • [36] Alight a beam and beaming light: A theme with variations
    Chattopadhyay, S
    PHYSICS OF PLASMAS, 1998, 5 (05) : 2081 - 2089
  • [37] Structures of BRAF-MEK1-14-3-3 sheds light on drug discovery
    Sun, Qiu
    Wang, Wenjing
    SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2019, 4 (1)
  • [38] PFIZER SHEDS VICURON AND CHOLESTEROL DRUG
    不详
    CHEMICAL & ENGINEERING NEWS, 2010, 88 (01) : 13 - 13
  • [39] Research Sheds Light on Superheating Mechanism
    Song Jianlan
    BulletinoftheChineseAcademyofSciences, 2001, (04) : 194 - 195
  • [40] Electronics sheds light on the vision sector
    Peach, Matthew
    Electronics World, 2005, 111 (1826): : 16 - 19