Luminescent Ag(I) scorpionates based on tris(2-pyridyl)phosphine oxide: Synthesis and cytotoxic activity evaluation

被引：24
|
作者：
Artem'ev, Alexander V. [1 ]
Eremina, Julia A. [1 ,2 ]
Lider, Elizaveta V. [1 ,2 ]
Antonova, Olga V. [1 ]
Vorontsova, Elena V. [3 ]
Bagryanskaya, Irina Yu. [2 ,4 ]
机构：
[1] Russian Acad Sci, Siberian Branch, Nikolaev Inst Inorgan Chem, 3 Akad Lavrentiev Ave, Novosibirsk 630090, Russia
[2] Natl Res Univ, Novosibirsk State Univ, Dept Nat Sci, 2 Pirogova Str, Novosibirsk 630090, Russia
[3] Inst Mol Biol & Biophys, 2-12 Timakova St, Novosibirsk 630117, Russia
[4] Russian Acad Sci, Siberian Branch, NN Vorozhtsov Novosibirsk Inst Organ Chem, 9 Akad Lavrentiev Ave, Novosibirsk 630090, Russia
来源：
POLYHEDRON | 2017年 / 138卷
基金：
俄罗斯基础研究基金会;
关键词：
Silver; Scorpionates; Luminescence; Cytotoxic activity; Tris(2-pyridyl)phosphine oxide; UNSUPPORTED SILVER-GERMANIUM; CATALYZED CARBENE INSERTION; ANTIMICROBIAL PROPERTIES; ETHYLENE COMPLEXES; ADDUCTS; LIGANDS; TRIS(PYRAZOLYL)BORATE; CARBONYL; COPPER; DERIVATIVES;
D O I：
10.1016/j.poly.2017.09.041
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
First representatives of Ag(I) scorpionates bearing tris(2-pyridyl)phosphine oxide (Py3P=O), viz. [Ag (Py3P=O)(PPh3)]BE4 (1) and [Ag(Py3P=O)(PPh3)]CIO4 (2), have been synthesized and structurally characterized. X-ray diffraction analysis reveals that the silver atom of 1 is coordinated by Py3P=O and Ph3P ligands in N,N',N"-tripodal and P-monodentate fashions, respectively. The both complexes exhibit significant cytotoxic activity (IC50 being from 11 to 14 mu M) screened in vitro against human larynx carcinoma (Hep-2) cell lines. The luminescent proprieties of the prepared scorpionates are also discussed. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码：218 / 224
页数：7
相关论文
共 50 条
  • [21] Synthesis and characterization of tris(2-pyridyl)phosphine oxide (OPPy3) complexes of select lanthanide(III) nitrates with potential application in molecular sensing
    Cox, Chandler
    Bezpalko, Mark
    Kassel, William
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 258
  • [22] Cu' and Ag' scorpionate-like complexes based on sterically hindered tris(6-methyl-2-pyridyl)phosphine oxide
    Demyanov, Yan V.
    Bagryanskaya, Irina Yu.
    Artem'ev, Alexander V.
    MENDELEEV COMMUNICATIONS, 2024, 34 (06) : 812 - 814
  • [23] Synthesis and characterization of a Ni(II)Au(I) bimetallic complex utilizing the Janus head ligand tris(2-pyridyl) phosphine [P(Py)3]
    Dougherty, WIlliam G.
    Kassel, W. Scott
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [24] Manganese(II), cobalts(II) and nickel(II) complexes of tris(2-pyridyl)phosphine and their catalytic activity toward oxidation of tetralin
    Kharat, Ali Nemati
    Jahromi, Bahareh Tamaddoni
    Bakhoda, Abolghasem
    TRANSITION METAL CHEMISTRY, 2012, 37 (01) : 63 - 69
  • [25] Manganese(II), cobalts(II) and nickel(II) complexes of tris(2-pyridyl)phosphine and their catalytic activity toward oxidation of tetralin
    Ali Nemati Kharat
    Bahareh Tamaddoni Jahromi
    Abolghasem Bakhoda
    Transition Metal Chemistry, 2012, 37 : 63 - 69
  • [26] Synthesis of tris(2-pyridyl)phosphine from red phosphorus and 2-bromopyridine in the CsF-NaOH-DMSO superbasic system
    Malysheva, S. F.
    Korocheva, A. O.
    Belogorlova, N. A.
    Artem'ev, A. V.
    Gusarova, N. K.
    Trofimov, B. A.
    DOKLADY CHEMISTRY, 2012, 445 : 164 - +
  • [27] Synthesis of tris(2-pyridyl)phosphine from red phosphorus and 2-bromopyridine in the CsF-NaOH-DMSO superbasic system
    S. F. Malysheva
    A. O. Korocheva
    N. A. Belogorlova
    A. V. Artem’ev
    N. K. Gusarova
    B. A. Trofimov
    Doklady Chemistry, 2012, 445 : 164 - 165
  • [28] Coordination chemistry of the Janus-head ligand tris(2-pyridyl)phosphine [P(Py)3] and its oxide with lanthanide nitrates
    Pericic, Danijel J.
    Suppa, Krystyn
    Dougherty, William G.
    Piro, Nicholas A.
    Kassel, W. Scott
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 248
  • [29] Coordination chemistry of the Janus-head ligand tris(2-pyridyl)phosphine [P(py)3] and its oxide with lanthanide nitrates
    Pericic, Danijel J.
    Dougherty, William G.
    Piro, Nicholas A.
    Kassel, W. Scott
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
  • [30] TRIS-(2-PYRIDYL) PHOSPHINE COMPLEXES OF RUTHENIUM(II) AND RHODIUM(I) - HYDROFORMYLATION OF HEX-1-ENE BY RHODIUM COMPLEXES
    KURTEV, K
    RIBOLA, D
    JONES, RA
    COLEHAMILTON, DJ
    WILKINSON, G
    JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1980, (01): : 55 - 58
12345