Dual-release hydrocortisone for treatment of adrenal insufficiency: a systematic review

被引：9

作者：

Mongioi, Laura Maria ^{[1
]}

Condorelli, Rosita Angela ^{[1
]}

Barbagallo, Federica ^{[1
]}

La Vignera, Sandro ^{[1
]}

Calogero, Aldo Eugenio ^{[1
]}

机构：

[1] Univ Catania, Dept Clin & Expt Med, Via S Sofia 78, I-95123 Catania, Italy

来源：

ENDOCRINE | 2020年 / 67卷 / 03期

关键词：

Adrenal insufficiency; Dual-release hydrocortisone; Pharmacokinetic; Metabolism; GLUCOCORTICOID REPLACEMENT REGIMENS; LONG-TERM SAFETY; QUALITY-OF-LIFE; ADDISONS-DISEASE; PROFILE; DIAGNOSIS; THERAPY;

D O I：

10.1007/s12020-020-02187-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Dual-release hydrocortisone is a new hydrocortisone formulation developed to improve the pharmacokinetic and the pharmacodynamic profiles and patient compliance. The aim of this review is to summarize the main knowledge on dual-release hydrocortisone, with particular attention to pharmacokinetics, metabolic and health-related quality-of-life aspects, bone health and drug safety.

引用

页码：507 / 515

页数：9

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