Dual-release hydrocortisone for treatment of adrenal insufficiency: a systematic review

被引：9
|
作者：
Mongioi, Laura Maria [1 ]
Condorelli, Rosita Angela [1 ]
Barbagallo, Federica [1 ]
La Vignera, Sandro [1 ]
Calogero, Aldo Eugenio [1 ]
机构：
[1] Univ Catania, Dept Clin & Expt Med, Via S Sofia 78, I-95123 Catania, Italy
来源：
ENDOCRINE | 2020年 / 67卷 / 03期
关键词：
Adrenal insufficiency; Dual-release hydrocortisone; Pharmacokinetic; Metabolism; GLUCOCORTICOID REPLACEMENT REGIMENS; LONG-TERM SAFETY; QUALITY-OF-LIFE; ADDISONS-DISEASE; PROFILE; DIAGNOSIS; THERAPY;
D O I：
10.1007/s12020-020-02187-7
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Dual-release hydrocortisone is a new hydrocortisone formulation developed to improve the pharmacokinetic and the pharmacodynamic profiles and patient compliance. The aim of this review is to summarize the main knowledge on dual-release hydrocortisone, with particular attention to pharmacokinetics, metabolic and health-related quality-of-life aspects, bone health and drug safety.
引用
收藏
页码：507 / 515
页数：9
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