Two new kaurane-type diterpenoids from Wedelia chinensis (Osbeck.) Merr

被引：7
|
作者：
Cai, Cancan [1 ,2 ]
Zhang, Yu [1 ]
Yang, Dongqiong [1 ,2 ]
Hao, Xiaojiang [1 ]
Li, Shunlin [1 ]
机构：
[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ci, Kunming, Yunnan, Peoples R China
[2] Univ Chinese Acad Sci, Beijing, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2017年 / 31卷 / 21期
基金：
中国国家自然科学基金;
关键词：
Wedelia chinensis; kauranetype diterpenoids; antibacterial activity; PROSTATE-CANCER; ASTERACEAE; EXTRACT; GROWTH;
D O I：
10.1080/14786419.2017.1317775
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two new kaurane-type diterpenoids, 3 alpha-(angeloyloxy)-17-hydroxyent-kaur-15-en-19-oic acid (1) and 3 alpha-(tigloyloxy)-17-hydroxy-entkaur- 15-en-19-oic acid (2), along with 10 known compounds (3-12) were isolated from the whole plant of Wedelia chinensis (Osbeck.) Merr. Their structures were elucidated on the basis of extensive spectroscopic analyses (UV, IR, MS and NMR) and comparison with literature data. Compounds 3 and 4 showed moderate inhibitory activity against the Staphylococcus aureus subsp. aureus ATCC29213 with MIC50 19.35 and 18.31 mu g/mL, respectively. [GRAPHICS] .
引用
收藏
页码：2531 / 2536
页数：6
相关论文
共 50 条
  • [31] Kaurane-type diterpene glycoside from the stem bark of Acanthopanax trifoliatus
    Kiem, PV
    Cai, XF
    Van Minh, C
    Lee, JJ
    Kim, YH
    PLANTA MEDICA, 2004, 70 (03) : 282 - 284
  • [32] BITTER KAURANE-TYPE DITERPENE GLUCOSIDES FROM THE LIVERWORT JUNGERMANNIA-INFUSCA
    NAGASHIMA, F
    TOYOTA, M
    ASAKAWA, Y
    PHYTOCHEMISTRY, 1990, 29 (05) : 1619 - 1623
  • [33] Two New ent-Kaurane Diterpenoids from the Roots of Fritillaria thunbergii
    Park, Jong Eel
    Lee, Seung Young
    Woo, Kyeong Wan
    Lee, Je Hyun
    Lee, Kang Ro
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2013, 34 (05) : 1589 - 1591
  • [34] Two new ent-kaurane diterpenoids from the leaves of Sphagneticola trilobata
    Ren, Hui
    Liu, Shao-Bo
    Lou, Tao
    Fu, Fen-Yu
    Xu, Qiao-Lin
    Zhang, Shan-Xuan
    Tan, Jian-Wen
    PHYTOCHEMISTRY LETTERS, 2022, 49 : 177 - 181
  • [35] Two New Compounds from Wedelia chinensis and Their Anti-inflammatory Activities
    Zhong, Yuan-Lin
    Zhang, Yu-Bo
    Luo, Ding
    Niu, Qian-Wen
    Qin, Juan
    He, Li-Jun
    Li, Yao-Lan
    Wang, Guo-Cai
    CHEMISTRYSELECT, 2018, 3 (12): : 3459 - 3462
  • [36] Two new terpenes from the aerial parts of Clematis chinensis Osbeck
    Sun Ye
    Liu Yan
    Sun, Yan-Ping
    Li, Xiao-Mao
    Wang Si-Yi
    Juan Pan
    Wei Guan
    Yuan Liu
    Naseem, Anam
    Yang, Bing-You
    Kuang, Hai-Xue
    NATURAL PRODUCT RESEARCH, 2022, 36 (15) : 3825 - 3832
  • [37] NEW KAURANE DITERPENOIDS FROM ASTER-TONGOLENSIS
    TAN, RX
    HU, YH
    LIU, ZL
    PAN, X
    JOURNAL OF NATURAL PRODUCTS, 1993, 56 (11): : 1917 - 1922
  • [38] Two new ent-kaurane diterpenes from the stems of Eurya chinensis
    Song, Jia-Ling
    Yuan, Yao
    Nie, Ling-Hui
    Li, Bai-Lin
    Qin, Xu-Bing
    Li, Yan
    Wu, Jie-Wei
    Qiu, Sheng-Xiang
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2018, 20 (10) : 962 - 968
  • [39] Structure of kaurane-type diterpenes from Parinari sprucei and their potential anticancer activity
    Braca, A
    Armenise, A
    Morelli, L
    Mendez, J
    Mi, QW
    Chai, HB
    Chai, HB
    Swanson, SM
    Kinghorn, AD
    Kinghorn, AD
    De Tommasi, N
    PLANTA MEDICA, 2004, 70 (06) : 540 - 550
  • [40] Two new ent-kaurane diterpenoids from the aerial parts of Isodon excisoides
    Jiao, Ke
    Li, Huo-Yun
    Zhang, Peng
    Pi, Hui-Fang
    Ruan, Han-Li
    Wu, Ji-Zhou
    CHINESE CHEMICAL LETTERS, 2014, 25 (01) : 131 - 133
12345