Proliferative glomerulonephritis with monoclonal immunoglobulin deposits associated with parvovirus B19

被引:6
|
作者
Santana de Roberts, Rosalba [1 ]
Batal, Ibrahim [2 ]
Aljareh, Amr [1 ]
Jim, Belinda [1 ]
机构
[1] Jacobi Med Ctr, Dept Med, Bronx, NY 10461 USA
[2] NewYork Presbyterian Hosp, Dept Pathol, New York, NY USA
关键词
nephrotic syndrome; proteinurea; immunology; drugs; infectious diseases; IGG DEPOSITS; INFECTION; PATIENT;
D O I
10.1136/bcr-2021-243061
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is included in the group of dysproteinaemias causing renal disease. Only a minority of cases are associated with a haematological malignancy. Two cases have been linked to acute parvovirus B19 infections. We report a 36-year-old African-American woman who presented with renal dysfunction, proteinuria, haematuria and a kidney biopsy reported as PGNMID with IgG3-kappa deposits. Her evaluation for a haematological malignancy was unrevealing. Her parvovirus IgM and IgG levels were positive. The patient was initially treated with an ACE inhibitor and spontaneously remitted with minimal proteinuria after 1 month. Repeat parvovirus B19 serologies 6 months later showed persistent IgG and DNA by PCR positivity but IgM negativity. Given the clinical scenario, we believe that her PGNMID was induced by acute parvovirus B19 infection, which appeared to resolve once her acute infection abated. In this report, we describe our latest understanding of PGNMID.
引用
收藏
页数:5
相关论文
共 50 条
  • [41] FAMILIAL CASES OF PROLIFERATIVE GLOMERULONEPHRITIS WITH MONOCLONAL IMMUNOGLOBULIN DEPOSITS ASSOCIATED WITH PGM3 DEFICIENCY
    Howard, Lilian
    Freeman, Alexandra F.
    Lyons, Jonathan J.
    Alexander, Mariam P.
    Waldman, Meryl
    AMERICAN JOURNAL OF KIDNEY DISEASES, 2020, 75 (04) : 587 - 587
  • [42] Proliferative glomerulonephritis with monoclonal immunoglobulin deposits: effects of pretreatment on posttransplant outcomes
    El Ters, Mireille
    Daum, Joshua
    Barbir, Elena-Bianca
    Nasr, Samih
    Leung, Nelson
    Amer, Hatem
    Said, Samar
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2024, 39
  • [43] Proliferative glomerulonephritis with monoclonal immunoglobulin G deposits complicated by immunoglobulin A nephropathy in the renal allograft
    Sawada, Anri
    Kawanishi, Kunio
    Horita, Shigeru
    Koike, Junki
    Honda, Kazuho
    Ochi, Ayami
    Komoda, Mizuki
    Tanaka, Yoichiro
    Unagami, Kohei
    Okumi, Masayoshi
    Shimizu, Tomokazu
    Ishida, Hideki
    Tanabe, Kazunari
    Nagashima, Yoji
    Nitta, Kosaku
    NEPHROLOGY, 2016, 21 : 48 - 52
  • [44] PARVOVIRUS B19 ASSOCIATED WITH PSEUDOAPPENDICITIS
    MORINET, F
    MONSUEZ, JJ
    ROGER, P
    PEROL, Y
    LANCET, 1987, 2 (8573): : 1466 - 1466
  • [45] Glomerulonephritis and Henoch-Schoenlein purpura associated with acute parvovirus B19 infection
    Díaz, F
    Collazos, J
    CLINICAL NEPHROLOGY, 2000, 53 (03) : 237 - 238
  • [46] Acute glomerulonephritis after human parvovirus B19 infection
    Nakazawa, T
    Tomosugi, N
    Sakamoto, K
    Asaka, M
    Yuri, T
    Ishikawa, I
    Kitagawa, S
    AMERICAN JOURNAL OF KIDNEY DISEASES, 2000, 35 (06)
  • [47] Proliferative Glomerulonephritis with Monoclonal IgG Deposits and Associated Hematopoietic Neoplasms
    Paueksakon, P.
    Fogo, A. B.
    MODERN PATHOLOGY, 2014, 27 : 414A - 414A
  • [48] Pregnancy-Associated Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposition
    Sinha, Ram
    Shah, Chintan Vimalkumar
    Belal, Amer Ashaab
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2024, 35 (10):
  • [49] Proliferative Glomerulonephritis with Monoclonal IgG Deposits and Associated Hematopoietic Neoplasms
    Paueksakon, P.
    Fogo, A. B.
    LABORATORY INVESTIGATION, 2014, 94 : 414A - 414A
  • [50] PROLIFERATIVE GLOMERULONEPHRITIS WITH MONOCLONAL IMMUNOGLOBULIN DEPOSITS OCCURRING AFTER STEM CELL TRANSPLANTATION
    Howard, Lilian
    Avila, Daniele
    Parta, Mark
    Hickstein, Dennis
    Alexander, Mariam
    Waldman, Meryl
    AMERICAN JOURNAL OF KIDNEY DISEASES, 2020, 75 (04) : 587 - 587