Synthesis of Allokainic Acid: A Review

被引:11
|
作者
Bhat, Chinmay [1 ]
Kumar, Amit [1 ]
机构
[1] Jain Univ, Ctr Nano & Mat Sci, Bangalore 562112, Karnataka, India
关键词
allokainic acid; kainic acid; kainoids; pyrrolidines; total synthesis; C-H INSERTION; CONFORMATIONALLY RESTRICTED ANALOGS; KUTZING CORSICAN-MOSS; ENE-TYPE REACTIONS; (+)-ALPHA-ALLOKAINIC ACID; FORMAL SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; AMINO-ACIDS; KAINIC ACID; STEREOSELECTIVE-SYNTHESIS;
D O I
10.1002/ajoc.201402250
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
This Focus Review discusses the synthesis of an important member of the kainoid family; allokainic acid. The members of the kainoid family have attracted worldwide attention since their first isolation in 1953 due to their vast and potential medicinal applications, especially in neuroscience. The review focuses on the synthesis of allokainic acid using different synthetic methods from its first synthesis to the most recent one, covering 1953-2014.
引用
收藏
页码:102 / 115
页数:14
相关论文
共 50 条
  • [41] Synthesis, biosynthesis and biological activities of galbanic acid - A review
    Kasaian, Jamal
    Iranshahy, Milad
    Iranshahi, Mehrdad
    PHARMACEUTICAL BIOLOGY, 2014, 52 (04) : 524 - 531
  • [42] Synthesis, Bioproduction and Bioactivity of Perillic Acid-A Review
    Rolim, Thais de Souza
    Sampaio, Andre Luiz Franco
    Mazzei, Jose Luiz
    Moreira, Davyson Lima
    Siani, Antonio Carlos
    MOLECULES, 2025, 30 (03):
  • [43] SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF GLUTAMIC ACID AMIDES: A REVIEW
    Voynikov, Y.
    Peikov, P.
    Tencheva, J.
    Zlatkov, Al.
    Stavrakov, G.
    PHARMACIA, 2012, 59 (1-4) : 85 - 95
  • [44] Synthesis and Bioactivity of (R)-Ricinoleic Acid Derivatives: A Review
    Pabis, Sylwia
    Kula, Jozef
    CURRENT MEDICINAL CHEMISTRY, 2016, 23 (35) : 4037 - 4056
  • [45] Iodoxybenzoic Acid (IBX) in Organic Synthesis: A Septennial Review
    Varala, Ravi
    Seema, Vittal
    Alam, Mohammed Mujahid
    Dubasi, Narsimhaswamy
    Vummadi, Rama Devi
    CURRENT ORGANIC SYNTHESIS, 2024, 21 (05) : 607 - 664
  • [46] Di- and Trisubstituted γ-Lactams via Rh(II)-carbenoid Reaction of N-Cα-Branched, N-Bis(trimethylsilyl)methyl α-Diazoamides. Synthesis of (±)-α-Allokainic Acid
    Zhang, Bao
    Wee, Andrew G. H.
    ORGANIC LETTERS, 2010, 12 (23) : 5386 - 5389
  • [47] Review: genetic background of milk fatty acid synthesis in bovines
    Singh, Akansha
    Malla, Waseem Akram
    Kumar, Amit
    Jain, Asit
    Thakur, Mohan Singh
    Khare, Vaishali
    Tiwari, Sita Prasad
    TROPICAL ANIMAL HEALTH AND PRODUCTION, 2023, 55 (05)
  • [48] Amino acid Gemini surfactants: a review on their synthesis, properties and applications
    Zhu, Sen
    Liu, Baowen
    Wang, Bin
    Liu, Lijuan
    TENSIDE SURFACTANTS DETERGENTS, 2025,
  • [49] Polylactic acid synthesis, biodegradability, conversion to microplastics and toxicity: a review
    Ali, Wajid
    Ali, Hazrat
    Gillani, Sayed
    Zinck, Philippe
    Souissi, Sami
    ENVIRONMENTAL CHEMISTRY LETTERS, 2023, 21 (03) : 1761 - 1786
  • [50] A Review on Synthesis, Properties, and Applications of Polylactic Acid/Silica Composites
    Kaseem, Mosab
    Ur Rehman, Zeeshan
    Hossain, Shakhawat
    Singh, Ashish Kumar
    Dikici, Burak
    POLYMERS, 2021, 13 (18)