Synthesis of Allokainic Acid: A Review

被引:11
|
作者
Bhat, Chinmay [1 ]
Kumar, Amit [1 ]
机构
[1] Jain Univ, Ctr Nano & Mat Sci, Bangalore 562112, Karnataka, India
关键词
allokainic acid; kainic acid; kainoids; pyrrolidines; total synthesis; C-H INSERTION; CONFORMATIONALLY RESTRICTED ANALOGS; KUTZING CORSICAN-MOSS; ENE-TYPE REACTIONS; (+)-ALPHA-ALLOKAINIC ACID; FORMAL SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; AMINO-ACIDS; KAINIC ACID; STEREOSELECTIVE-SYNTHESIS;
D O I
10.1002/ajoc.201402250
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
This Focus Review discusses the synthesis of an important member of the kainoid family; allokainic acid. The members of the kainoid family have attracted worldwide attention since their first isolation in 1953 due to their vast and potential medicinal applications, especially in neuroscience. The review focuses on the synthesis of allokainic acid using different synthetic methods from its first synthesis to the most recent one, covering 1953-2014.
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页码:102 / 115
页数:14
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