A Synthesis of Dihydrofuran-3(2H)-ones

被引：10

作者：

Tata, Rama Rao ^{[1
]}

Harmata, Michael ^{[1
]}

机构：

[1] Univ Missouri, Dept Chem, Columbia, MO 65211 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 80卷 / 13期

关键词：

MICHAEL ADDITION-REACTIONS; ALGA LAURENCIA-CHILENSIS; STEREOSELECTIVE-SYNTHESIS; RING-CLOSURE; SUBSTITUTED TETRAHYDROFURANS; 5-ENDO-TRIG CYCLIZATION; GEIPARVARIN ANALOGS; GEIJERA-PARVIFLORA; XYLARIA-LONGIANA; DERIVATIVES;

D O I：

10.1021/acs.joc.5b01076

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of readily available alpha '-hydroxyenones with a catalytic amount of strong acid in refluxing toluene affords the corresponding dihydrofuran-3(2H)-ones in excellent yields via a formal 5-endo-trig cyclization.

引用

页码：6839 / 6845

页数：7

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