A Synthesis of Dihydrofuran-3(2H)-ones

被引：10
|
作者：
Tata, Rama Rao [1 ]
Harmata, Michael [1 ]
机构：
[1] Univ Missouri, Dept Chem, Columbia, MO 65211 USA
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 80卷 / 13期
关键词：
MICHAEL ADDITION-REACTIONS; ALGA LAURENCIA-CHILENSIS; STEREOSELECTIVE-SYNTHESIS; RING-CLOSURE; SUBSTITUTED TETRAHYDROFURANS; 5-ENDO-TRIG CYCLIZATION; GEIPARVARIN ANALOGS; GEIJERA-PARVIFLORA; XYLARIA-LONGIANA; DERIVATIVES;
D O I：
10.1021/acs.joc.5b01076
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Treatment of readily available alpha '-hydroxyenones with a catalytic amount of strong acid in refluxing toluene affords the corresponding dihydrofuran-3(2H)-ones in excellent yields via a formal 5-endo-trig cyclization.
引用
收藏
页码：6839 / 6845
页数：7
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