Cytokine induction and growth inhibition of primary human cells expressing TLR3 is observed for long double-stranded RNA, but not siRNA

被引:0
|
作者
John, Matthias [1 ]
Jahn-Hofmann, Kerstin [1 ]
Hadwiger, Philipp [1 ]
Vornlocher, Hans-Peter [1 ]
机构
[1] Roche Kulmbach GmbH, D-95326 Kulmbach, Germany
关键词
D O I
10.1016/j.cyto.2011.07.171
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:66 / 66
页数:1
相关论文
共 50 条
  • [41] Human host defense peptide LL-37 facilitates double-stranded RNA pro-inflammatory signaling through up-regulation of TLR3 expression in vascular smooth muscle cells
    Dahl, Sara
    Cerps, Samuel
    Rippe, Catarina
    Sward, Karl
    Uller, Lena
    Svensson, Daniel
    Nilsson, Bengt-Olof
    INFLAMMATION RESEARCH, 2020, 69 (06) : 579 - 588
  • [42] ARE DOUBLE-STRANDED RNA-DIRECTED INHIBITION OF PROTEIN-SYNTHESIS IN INTERFERON-TREATED CELLS AND INTERFERON INDUCTION RELATED PHENOMENA
    TORRENCE, PF
    FRIEDMAN, RM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1979, 254 (04) : 1259 - 1267
  • [43] Muc1 Prevents Virus-Derived Double-Stranded Rna-Induced Epithelial Cell Inflammation And Apoptosis By Inhibiting Recruitment Of Trif To Tlr3
    Kato, K.
    Kim, K. C.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2013, 187
  • [44] Double-stranded RNA upregulates the expression of inflammatory mediators in human aortic valve cells through the TLR3-TRIF-noncanonical NF-κB pathway
    Zhan, Qiong
    Song, Rui
    Li, Fei
    Ao, Lihua
    Zeng, Qingchun
    Xu, Dingli
    Fullerton, David A.
    Meng, Xianzhong
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2017, 312 (04): : C407 - C417
  • [45] Effects of Brazilian green propolis on double-stranded RNA-mediated induction of interferon-inducible gene and inhibition of recruitment of polymorphonuclear cells
    Hayakari, Ryo
    Matsumiya, Tomoh
    Xing, Fei
    Tayone, Janeth C.
    Dempoya, Junichi
    Tatsuta, Tetsuya
    Aizawa-Yashiro, Tomomi
    Imaizumi, Tadaatsu
    Yoshida, Hidemi
    Satoh, Kei
    JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2013, 93 (03) : 646 - 651
  • [46] IFN-γ Primes Intact Human Coronary Arteries and Cultured Coronary Smooth Muscle Cells to Double-Stranded RNA- and Self-RNA-Induced Inflammatory Responses by Upregulating TLR3 and Melanoma Differentiation-Associated Gene 5
    Ahmad, Usman
    Ali, Rahmat
    Lebastchi, Amir H.
    Qin, Lingfeng
    Lo, Sheng-fu L.
    Yakimov, Alexander O.
    Khan, Salman F.
    Choy, Jonathan C.
    Geirsson, Arnar
    Pober, Jordan S.
    Tellides, George
    JOURNAL OF IMMUNOLOGY, 2010, 185 (02): : 1283 - 1294
  • [47] Protein kinase R regulates double-stranded RNA induction of TNF-α but not IL-1β mRNA in human epithelial cells
    Meusel, TR
    Kehoe, KE
    Imani, F
    JOURNAL OF IMMUNOLOGY, 2002, 168 (12): : 6429 - 6435
  • [48] Double-Stranded RNA Stimulates TLR3-Dependent Upregulation of IL-33 Transcript and Protein in Pulmonary Microvascular Endothelial Cells
    Matsuda, Akio
    Sugie, Maiko
    Shoda, Tetsuo
    Futamura, Kyoko
    Saito, Hirohisa
    Matsumoto, Kenji
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2015, 135 (02) : AB145 - AB145
  • [49] GROWTH-RELATED EXPRESSION OF A DOUBLE-STRANDED RNA-DEPENDENT PROTEIN-KINASE IN 3T3 CELLS
    PETRYSHYN, R
    CHEN, JJ
    LONDON, IM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1984, 259 (23) : 4736 - 4742
  • [50] Chitinase 3-like 1 is involved in the induction of IL-8 expression by double-stranded RNA in airway epithelial cells
    Lee, Jae Woo
    Kim, Mi Na
    Kim, Eun Gyul
    Leem, Ji Su
    Baek, Seung Min
    Kim, Min Jung
    Kim, Kyung Won
    Sohn, Myung Hyun
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022, 592 : 106 - 112