Cytokine induction and growth inhibition of primary human cells expressing TLR3 is observed for long double-stranded RNA, but not siRNA

被引：0
|
作者：
John, Matthias [1 ]
Jahn-Hofmann, Kerstin [1 ]
Hadwiger, Philipp [1 ]
Vornlocher, Hans-Peter [1 ]
机构：
[1] Roche Kulmbach GmbH, D-95326 Kulmbach, Germany
来源：
CYTOKINE | 2011年 / 56卷 / 01期
关键词：
D O I：
10.1016/j.cyto.2011.07.171
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：66 / 66
页数：1
相关论文
共 50 条
  • [21] Distinct roles for MDA5 and TLR3 in the acute response to inhaled double-stranded RNA
    Veazey, Janelle M.
    Chapman, Timothy J.
    Smyth, Timothy R.
    Hillman, Sara E.
    Eliseeva, Sophia I.
    Georas, Steve N.
    PLOS ONE, 2019, 14 (05):
  • [22] Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling
    Saumendra N Sarkar
    Kristi L Peters
    Christopher P Elco
    Shuji Sakamoto
    Srabani Pal
    Ganes C Sen
    Nature Structural & Molecular Biology, 2004, 11 : 1060 - 1067
  • [23] Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling
    Sarkar, SN
    Peters, KL
    Elco, CP
    Sakamoto, S
    Pal, S
    Sen, GC
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2004, 11 (11) : 1060 - 1067
  • [24] TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction
    Sakaniwa, Kentaro
    Fujimura, Akiko
    Shibata, Takuma
    Shigematsu, Hideki
    Ekimoto, Toru
    Yamamoto, Masaki
    Ikeguchi, Mitsunori
    Miyake, Kensuke
    Ohto, Umeharu
    Shimizu, Toshiyuki
    NATURE COMMUNICATIONS, 2023, 14 (01)
  • [25] TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction
    Kentaro Sakaniwa
    Akiko Fujimura
    Takuma Shibata
    Hideki Shigematsu
    Toru Ekimoto
    Masaki Yamamoto
    Mitsunori Ikeguchi
    Kensuke Miyake
    Umeharu Ohto
    Toshiyuki Shimizu
    Nature Communications, 14 (1)
  • [26] Mannan binding lectin attenuates double-stranded RNA-mediated TLR3 activation and innate immunity
    Liu, Hongzhi
    Zhou, Jia
    Ma, Di
    Lu, Xiao
    Ming, Siqi
    Shan, Guiqiu
    Zhang, Xiaoyong
    Hou, Jinlin
    Chen, Zhengliang
    Zuo, Daming
    FEBS LETTERS, 2014, 588 (06): : 866 - 872
  • [27] Respiratory Syncytial Virus Or The Tlr3 Ligand Double Stranded Rna Induce Glucocorticoid Resistance In Human Bronchial Epithelial Cells
    Radwan, A.
    Xia, Y. C.
    Langenbach, S.
    Gualano, R. C.
    Stewart, A. G.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016, 193
  • [28] Respiratory Syncytial Virus Or The Tlr3 Ligand, Double Stranded Rna, Induce Glucocorticoid Resistance In Human Bronchial Epithelial Cells
    Stewart, A. G.
    Radwan, A.
    Xia, Y.
    Langenbach, S.
    Gualano, R. C.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016, 193
  • [29] TLR3, TRIF, and Caspase 8 Determine Double-Stranded RNA-Induced Epithelial Cell Death and Survival In Vivo
    McAllister, Christopher S.
    Lakhdari, Omar
    de Chambrun, Guillaume Pineton
    Gareau, Melanie G.
    Broquet, Alexis
    Lee, Gin Hyug
    Shenouda, Steven
    Eckmann, Lars
    Kagnoff, Martin F.
    JOURNAL OF IMMUNOLOGY, 2013, 190 (01): : 418 - 427
  • [30] Double-stranded RNA signals antiviral and inflammatory programs and dysfunctional glutamate transport in TLR3-expressing astrocytes
    Scumpia, PO
    Kelly, SM
    Reeves, WH
    Stevens, BR
    GLIA, 2005, 52 (02) : 153 - 162
12345