Capilloquinol: A Novel Farnesyl Quinol from the Dongsha Atoll Soft Coral Sinularia capillosa

被引：28
|
作者：
Cheng, Shi-Yie [2 ]
Huang, Ki-Jhih [2 ]
Wang, Shang-Kwei [1 ]
Duh, Chang-Yih [2 ,3 ,4 ]
机构：
[1] Kaohsiung Med Univ, Dept Microbiol, Kaohsiung 807, Taiwan
[2] Natl Sun Yat Sen Univ, Dept Marine Biotechnol & Resources, Kaohsiung 804, Taiwan
[3] Natl Sun Yat Sen Univ, Ctr Asia Pacific Ocean Res, Kaohsiung 804, Taiwan
[4] Natl Sun Yat Sen Univ, Ctr Translat Biopharmaceut, Kaohsiung 804, Taiwan
来源：
MARINE DRUGS | 2011年 / 9卷 / 09期
关键词：
soft coral; Sinularia capillosa; farnesyl quinoid; cytotoxicity; MARINE SPONGE; APLIDIUM-LONGITHORAX; DERIVATIVES;
D O I：
10.3390/md9091469
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Capilloquinol (1), possessing an unprecedented farnesyl quinoid skeleton, was isolated from the Dongsha Atoll soft coral Sinularia capillosa. The structure of capilloquinol was elucidated by extensive analysis of spectroscopic data. The cytotoxicity and antiviral activity against human cytomegalovirus of 1 was evaluated in vitro.
引用
收藏
页码：1469 / 1476
页数：8
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