Capilloquinol: A Novel Farnesyl Quinol from the Dongsha Atoll Soft Coral Sinularia capillosa

被引：28
|
作者：
Cheng, Shi-Yie [2 ]
Huang, Ki-Jhih [2 ]
Wang, Shang-Kwei [1 ]
Duh, Chang-Yih [2 ,3 ,4 ]
机构：
[1] Kaohsiung Med Univ, Dept Microbiol, Kaohsiung 807, Taiwan
[2] Natl Sun Yat Sen Univ, Dept Marine Biotechnol & Resources, Kaohsiung 804, Taiwan
[3] Natl Sun Yat Sen Univ, Ctr Asia Pacific Ocean Res, Kaohsiung 804, Taiwan
[4] Natl Sun Yat Sen Univ, Ctr Translat Biopharmaceut, Kaohsiung 804, Taiwan
来源：
MARINE DRUGS | 2011年 / 9卷 / 09期
关键词：
soft coral; Sinularia capillosa; farnesyl quinoid; cytotoxicity; MARINE SPONGE; APLIDIUM-LONGITHORAX; DERIVATIVES;
D O I：
10.3390/md9091469
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Capilloquinol (1), possessing an unprecedented farnesyl quinoid skeleton, was isolated from the Dongsha Atoll soft coral Sinularia capillosa. The structure of capilloquinol was elucidated by extensive analysis of spectroscopic data. The cytotoxicity and antiviral activity against human cytomegalovirus of 1 was evaluated in vitro.
引用
收藏
页码：1469 / 1476
页数：8
相关论文
共 50 条
  • [21] Bioactive Cembranoids, Sarcocrassocolides P-R, from the Dongsha Atoll Soft Coral Sarcophyton crassocaule
    Lin, Wan-Yu
    Chen, Bo-Wei
    Huang, Chiung-Yao
    Wen, Zhi-Hong
    Sung, Ping-Jyun
    Su, Jui-Hsin
    Dai, Chang-Feng
    Sheu, Jyh-Horng
    MARINE DRUGS, 2014, 12 (02): : 840 - 850
  • [22] Sarcophytonins F and G, New Dihydrofuranocembranoids from a Dongsha Atoll Soft Coral Sarcophyton sp.
    Chen, Shin-Pin
    Chen, Bo-Wei
    Dai, Chang-Feng
    Sung, Ping-Jyun
    Wu, Yang-Chang
    Sheu, Jyh-Horng
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 2012, 85 (08) : 920 - 922
  • [23] Sarcocrassocolides M-O, Bioactive Cembranoids from the Dongsha Atoll Soft Coral Sarcophyton crassocaule
    Lin, Wan-Yu
    Lu, Yi
    Chen, Bo-Wei
    Huang, Chiung-Yao
    Su, Jui-Hsin
    Wen, Zhi-Hong
    Dai, Chang-Feng
    Kuo, Yao-Haur
    Sheu, Jyh-Horng
    MARINE DRUGS, 2012, 10 (03) : 617 - 626
  • [24] A FARNESYL ARABINOSIDE AS AN ENHANCER OF GLUCOSE-TRANSPORT IN RAT ADIPOCYTES FROM A SOFT CORAL, SINULARIA SP
    SHINDO, T
    SATO, A
    HORIKOSHI, H
    KUWANO, H
    EXPERIENTIA, 1992, 48 (07): : 688 - 690
  • [25] Abruptoside A, A novel glycolipid from the Kenyan soft coral Sinularia abrupta
    Shmul, Guy
    Benayahu, Yehuda
    Kashrnan, Yoel
    NATURAL PRODUCT COMMUNICATIONS, 2007, 2 (01) : 51 - 54
  • [26] A novel polyhydroxylated epoxy steriod from the soft coral Sinularia dissecta
    Venkateswarlu, Y
    Ramesh, P
    Reddy, NS
    Rao, TP
    NATURAL PRODUCT LETTERS, 1999, 13 (03): : 229 - 232
  • [27] A novel diketosesquiterpenoid from the soft coral Sinularia intacta of the Indian Ocean
    Anjaneyulu, ASR
    Gowri, PM
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1999, 38 (01): : 4 - 7
  • [28] A novel cytotoxic norditerpenoid from the Formosan soft coral Sinularia inelegans
    Duh, CY
    Wang, SK
    Chia, MC
    Chiang, MY
    TETRAHEDRON LETTERS, 1999, 40 (33) : 6033 - 6035
  • [29] Mollisolactones A and B, novel dinormonoterpenes from the soft coral Sinularia mollis
    Cheng, Shi-Yie
    Wang, Shang-Kwei
    Ou, Yih-Hsin
    Duh, Chang-Yih
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 26 (03) : 879 - 881
  • [30] A novel cytotoxic biscembranoid from the formosan soft coral Sinularia flexibilis
    Duh, CY
    Wang, SK
    Tseng, HK
    Sheu, JH
    TETRAHEDRON LETTERS, 1998, 39 (39) : 7121 - 7122
12345