In vitro cytotoxicity of monodispersed hematite nanoparticles on Hek 293 cells

被引：26
|
作者：
Yan, Haijuan [1 ,2 ]
Zhang, Benshu [1 ]
机构：
[1] Tianjin Med Univ, Tianjin 300070, Peoples R China
[2] Univ Gottingen, D-37075 Gottingen, Germany
来源：
MATERIALS LETTERS | 2011年 / 65卷 / 05期
关键词：
Hematite nanoparticles; Hydrothermal; Monodispersion; Cytotoxicity; Oxidative stress; SIZE;
D O I：
10.1016/j.matlet.2010.12.004
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
A simple hydrothermal method was developed to prepare monodispersed and well-crystallized hematite nanoparticles with a diameter distribution of about 180 nm. In-vitro cytotoxicity of such nanoparticles was carried out using Hek 293 cell culture system with different dosages. Assessment of cell viability reveals that hematite nanoparticles reduce cell viability in a dose- and time-dependent manner within a rather wide dosage range. Such cytotoxicity is correlative Lathe decrease of the activity of antioxidative enzymes induced by the oxidative stress in cells. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码：815 / 817
页数：3
相关论文
共 50 条
  • [41] Effect of PTTG on endogenous gene expression in HEK 293 cells
    Panguluri, Siva K.
    Kakar, Sham S.
    BMC GENOMICS, 2009, 10
  • [42] Internalization and cointernalization of heterologous opioid receptors in HEK 293 cells
    Schulz, R
    Wehmeyer, A
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2002, 365 : R35 - R35
  • [43] Analysis of DNA topology of EBV minichromosomes in HEK 293 cells
    Castan, Alicia
    Fernandez-Calleja, Vanessa
    Hernandez, Pablo
    Krimer, Dora B.
    Schvartzman, Jorge B.
    Fernandez-Nestosa, Maria-Jose
    PLOS ONE, 2017, 12 (11):
  • [44] Expression of concatemerized neurotransmitter transporters in HEK293 cells
    Seidel, S
    Scholze, P
    Holy, M
    Freissmuth, M
    Singer, EA
    Sitte, HH
    Kudlacek, O
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2003, 367 : R5 - R5
  • [45] Effect of PTTG on endogenous gene expression in HEK 293 cells
    Siva K Panguluri
    Sham S Kakar
    BMC Genomics, 10
  • [46] Production of recombinant antitumor antibodies by HEK-293 cells
    Deyev S.M.
    Stremovskiy O.A.
    Lukash S.V.
    Karpenko D.V.
    Polyanovsky O.L.
    Petrov R.V.
    Doklady Biochemistry and Biophysics, 2006, 406 (1) : 44 - 46
  • [47] Micropatterned surfaces of PDMS as growth templates for HEK 293 cells
    R. M. Johann
    Ch. Baiotto
    Ph. Renaud
    Biomedical Microdevices, 2007, 9 : 475 - 485
  • [48] Ultrastructural Features of Gold Nanoparticles Interaction with HepG2 and HEK293 Cells in Monolayer and Spheroids
    Chelobanov, Boris
    Poletaeva, Julia
    Epanchintseva, Anna
    Tupitsyna, Anastasiya
    Pyshnaya, Inna
    Ryabchikova, Elena
    NANOMATERIALS, 2020, 10 (10) : 1 - 23
  • [49] Intercellular transfer of plasmid DNA between in vitro cultured HEK293 cells following transient transfection
    Gerdes, Christoph
    Basmanav, F. Buket
    PLASMID, 2024, 131
  • [50] In Vitro Toxicity Evaluation of Cyanotoxins Cylindrospermopsin and Microcystin-LR on Human Kidney HEK293 Cells
    Diez-Quijada, Leticia
    Puerto, Maria
    Gutierrez-Praena, Daniel
    Turkina, Maria, V
    Campos, Alexandre
    Vasconcelos, Vitor
    Camean, Ana M.
    Jos, Angeles
    TOXINS, 2022, 14 (07)
12345