Nonparametric estimation of survival functions by means of partial exchangeability structures

被引:1
|
作者
Giudici, P
Mezzetti, M
机构
[1] Univ Pavia, Dipartimento Econ Polit & Metodi Quantitat, I-27100 Pavia, Italy
[2] European Inst Oncol, I-20141 Milan, Italy
关键词
beta processes; hierarchical partition models; posterior probabilities; survival analysis;
D O I
10.1007/BF02565105
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
In the causal analysis of survival data a time-based response is related to a set of explanatory variables. However, selection and proper design of the latter may become a difficult task, particularly in the preliminary stage, when the information is limited. We propose an alternative nonparametric approach to estimate the survival function which allows one to evaluate the relative importance of each potential explanatory variable, in a simple and exploratory fashion. To achieve this aim, each of the explanatory variables is used to partition the observed survival times. The observations are assumed to be partially exchangeable according to such partition. We then consider, conditionally on each partition, a hierarchical nonparametric Bayesian model on the hazard functions. In order to measure the importance of each explanatory variable, we derive the posterior probability of the corresponding partition. Such probabilities are then employed to estimate the hazard functions by averaging the estimated conditional hazard over the set of all entertained partitions.
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页码:111 / 132
页数:22
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