Effect of Randomly Interesterified Triacylglycerol Containing Medium- and Long-Chain Fatty Acids on Hepatic Fatty Acid Oxidation after a Single Administration to Rats

被引:5
|
作者
Shinohara, Hisami [1 ]
Wu, Jian [1 ]
Aoyama, Toshiaki [1 ]
机构
[1] Nisshin OilliO Grp Ltd, Cent Res Lab, Kanagawa 2390832, Japan
关键词
medium-chain fatty acid; fatty acid oxidation; acyl-CoA dehydrogenase; DIETARY MEDIUM-CHAIN; ENERGY-EXPENDITURE; BODY-FAT; TRIGLYCERIDES; METABOLISM; ACCUMULATION; LIVER; COA;
D O I
10.1271/bbb.100412
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
MLCTs, which are randomly interesterified triacylglycerol containing medium- and long-chain fatty acids in the same glycerol molecule, showed significantly higher acyl-CoA dehydrogenase activity when measured by using butyryl-CoA, octanoyl-CoA, and palmitoyl-CoA as substrates than long-chain triacylglycerol one hour after a single administration to rats. These results suggest that not only medium-chain fatty acid oxidation, but also long-chain fatty acid oxidation were increased in the liver of rats administered with MLCT.
引用
收藏
页码:2336 / 2338
页数:3
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