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T cell receptors get back to basics
被引：3
|作者：
Jones, E. Yvonne
[1
]
Salio, Mariolina
Cerundolo, Vincenzo
机构：
[1] Henry Wellcome Bldg Genomic Med, Canc Res UK Receptor Struct Res Grp, Oxford OX3 7BN, England
[2] Univ Oxford, Weather Inst Mol Med, Nuffield Dept Med, Canc Res UK Tumor Immunol Grp, Oxford OX3 9DS, England
基金：
英国医学研究理事会;
关键词：
D O I：
10.1038/ni1007-1033
中图分类号：
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
For both mice and humans, an invariant T cell receptor mediates the recognition of glycolipid antigens presented in the context of CD1d molecules. Crystal structure and mutagenesis-based analyses now identify a minimalist binding mode well suited to an 'innate-style' pattern-recognition function.
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页码：1033 / 1035
页数：3
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