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Single-Molecule Spectroscopy Illuminating the Molecular Dynamics of Life
被引:3
|作者:
Webb, Watt W.
[1
]
机构:
[1] Cornell Univ, Sch Appl & Engn Phys, Ithaca, NY 14853 USA
来源:
关键词:
FLUORESCENCE CORRELATION SPECTROSCOPY;
RNA-POLYMERASE-II;
MULTIPHOTON MICROSCOPY;
PROTEIN;
FLUCTUATIONS;
DIFFUSION;
RECEPTORS;
EMISSION;
PLAQUES;
BINDING;
D O I:
10.1007/978-3-642-02597-6_5
中图分类号:
O65 [分析化学];
学科分类号:
070302 ;
081704 ;
摘要:
This chapter summarizes a series of new single-molecule spectroscopy investigations in the life sciences at Cornell University that began with our invention of Fluorescence Correlation Spectroscopy (FCS) about 1970. Our invention of FCS became my first focus on the "Molecular Dynamics of Life." It motivated my transition from research on quantum fluctuations and transport in condensed matter physics including superconductivity and in the molecular dynamics of coherent fluctuations and nano-transport in inanimate physical and chemical systems subject to the nonlinear dynamics of continuous phase transitions. These interdisciplinary transitions exemplify the productivity of such interdisciplinary interactions in science.
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页码:107 / 117
页数:11
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