Aromatic nucleophilic substitution in 1,2,4-triazine 4-oxides with Grignard reagents

被引：0
|
作者：
Prokhorov, AM [1 ]
Kozhevnikov, DN [1 ]
Rusinov, VL [1 ]
Chupakhin, ON [1 ]
机构：
[1] Urals State Tech Univ, Ekaterinburg 620002, Russia
来源：
POLISH JOURNAL OF CHEMISTRY | 2003年 / 77卷 / 09期
关键词：
1,2,4-triazines; Grignard reagents; sigma-adducts; aromatization; dehydrogenation; regioselectivity; heterocycles;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Addition of the Grignard reagents to 1,2,4-triazine 4-oxides followed by aromatization of the intermediate sigma(H)-adducts by dehydrogenation or dehydration was used for synthesis of 5-alkyl- or 5-aryl-substituted 1,2,4-triazines and their 4-oxides.
引用
收藏
页码：1157 / 1161
页数：5
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