Aromatic nucleophilic substitution in 1,2,4-triazine 4-oxides with Grignard reagents

被引：0

作者：

Prokhorov, AM ^{[1
]}

Kozhevnikov, DN ^{[1
]}

Rusinov, VL ^{[1
]}

Chupakhin, ON ^{[1
]}

机构：

[1] Urals State Tech Univ, Ekaterinburg 620002, Russia

来源：

POLISH JOURNAL OF CHEMISTRY | 2003年 / 77卷 / 09期

关键词：

1,2,4-triazines; Grignard reagents; sigma-adducts; aromatization; dehydrogenation; regioselectivity; heterocycles;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Addition of the Grignard reagents to 1,2,4-triazine 4-oxides followed by aromatization of the intermediate sigma(H)-adducts by dehydrogenation or dehydration was used for synthesis of 5-alkyl- or 5-aryl-substituted 1,2,4-triazines and their 4-oxides.

引用

页码：1157 / 1161

页数：5

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