New tetralone acid intermediates for the synthesis of β-apopicropodophyllin analogues

被引：0
|
作者：
Sadashivamurthy, B. [1 ]
Basavaraju, Y. B. [1 ]
Sathisha, A. D. [1 ]
Hemakumar, K. H. [1 ]
机构：
[1] Univ Mysore, Dept Studies Chem, Mysore 570006, Karnataka, India
来源：
BULGARIAN CHEMICAL COMMUNICATIONS | 2007年 / 39卷 / 04期
关键词：
berizophenones; Stobbe condensation; itaconic acids; sodium amalgam; benzhydrylsuccinic acids and tetralone acids;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
New tetralone acid intermediates 3-carboxy-4-(p-tolyl)-6,7-dimethoxy-1-tetralone, 3-carboxy-4-(P-tolyl)-6-methyl-7-methoxy-1-tetralone and 3-carboxy-4-(p-tolyl)-6-chloro-7-methoxy-1-tetralone were synthesized in high yields by Gensler's route with some change in reagents. They are very essential for the synthesis and study of antimitotic activity of beta-apopicropodophyllin analogues. All the products were characterized by spectral and elemental analysis data.
引用
收藏
页码：264 / 268
页数：5
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