Ruthenium-catalyzed 1,2,3-triazole directed intermolecular C-H amidation of arenes with sulfonyl azides

被引：26
|
作者：
Wang, Xiaoyu
Zhang, Chen
Li, Jue
Jiang, Chong
Su, Fu
Zhan, Zhen
Hai, Li
Chen, Zhonghua [1 ]
Wu, Yong [1 ]
机构：
[1] Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting, Educ Minist, Chengdu 610041, Peoples R China
来源：
RSC ADVANCES | 2016年 / 6卷 / 73期
基金：
中国国家自然科学基金;
关键词：
ROOM-TEMPERATURE; BOND ACTIVATION; 2-SUBSTITUTED 1,2,3-TRIAZOLES; PROTECTED ARYLAMINES; RECEPTOR ANTAGONIST; COUPLING REACTIONS; DIRECT ARYLATIONS; AROMATIC KETONES; CUPRIC ACETATE; ORGANIC AZIDES;
D O I：
10.1039/c6ra14020c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Synthesis of 2-(2H-1,2,3-triazole-2-yl) aniline derivatives from 2-aryl-1,2,3-triazoles and sulfonylazides through ruthenium-catalyzed intermolecular C-H amidation is achieved. This reaction provides an environmentally benign protocol for C-N bond formation, producing N-2 gas as the sole byproduct. Yet a number of functionalities are well tolerated, obtaining the desired products in moderate to excellent yields.
引用
收藏
页码：68929 / 68933
页数：5
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