Effect of in vivo hypoxic preconditioning on changes in intracellular calcium content induced by long-term anoxia in rat brain slices

被引：7
|
作者：
Semenov, DG [1 ]
Miller, OL [1 ]
Samoilov, MO [1 ]
机构：
[1] Russian Acad Sci, IP Pavlov Physiol Inst, St Petersburg 196140, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2004年 / 138卷 / 04期
关键词：
hypobaric hypoxia; preconditioning; calcium; brain slices;
D O I：
10.1007/s10517-005-0093-9
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
We studied changes in intracellular calcium content induced by 10-min anoxia in olfactory cortex slices from rats exposed to single or 3-fold moderate hypobaric hypoxia ("ascend" at 5000 in). Repeated preconditioning with moderate hypobaric hypoxia produced a neuroprotective effect. This treatment abolished pathological calcium overload in brain slices induced in vitro by 10-min test anoxia.
引用
收藏
页码：338 / 340
页数：3
相关论文
共 50 条
  • [31] Functional changes in long-term incubated rat precision-cut lung slices
    Sarah Marie Nußbaum
    Julia Krabbe
    Svenja Böll
    Aaron Babendreyer
    Christian Martin
    Respiratory Research, 23
  • [32] Optimization of behavioral testing in a long-term rat model of hypoxic ischemic brain injury
    Penny, Tayla R.
    Pham, Yen
    Sutherland, Amy E.
    Smith, Madeleine J.
    Lee, Joohyung
    Jenkin, Graham
    Fahey, Michael C.
    Miller, Suzanne L.
    McDonald, Courtney A.
    BEHAVIOURAL BRAIN RESEARCH, 2021, 409
  • [33] ASSESSMENT OF LONG-TERM EFFECTS OF TRANSIENT ANOXIA ON METABOLIC-ACTIVITY OF RAT HIPPOCAMPAL SLICES USING TRIPHENYLTETRAZOLIUM CHLORIDE
    WATSON, GB
    LOPEZ, OT
    CHARLES, VD
    LANTHORN, TH
    JOURNAL OF NEUROSCIENCE METHODS, 1994, 53 (02) : 203 - 208
  • [34] CHANGES OF CALCIUM-METABOLISM IN RAT-TISSUES DURING LONG-TERM ANESTHESIA INDUCED BY INACTIN
    HEITZ, C
    STOCLET, JC
    JOURNAL DE PHARMACOLOGIE, 1980, 11 (01) : 90 - 91
  • [35] Lipopolysaccharide Preconditioning Reduces Neuroinflammation Against Hypoxic Ischemia and Provides Long-Term Outcome of Neuroprotection in Neonatal Rat
    Lin, Hsiang-Yin
    Huang, Chao-Ching
    Chang, Kang-Fan
    PEDIATRIC RESEARCH, 2009, 66 (03) : 254 - 259
  • [36] Lipopolysaccharide Preconditioning Reduces Neuroinflammation Against Hypoxic Ischemia and Provides Long-Term Outcome of Neuroprotection in Neonatal Rat
    Hsiang-Yin Lin
    Chao-Ching Huang
    Kang-Fan Chang
    Pediatric Research, 2009, 66 : 254 - 259
  • [37] CHANGES OF INTRACELLULAR CATION CONTENT IN MUSCULAR TISSUES OF RAT FOLLOWING AN ACUTE CALCIUM LOAD IN-VIVO
    LUTH, B
    WESTPHAL, W
    PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1973, 339 : R52 - R52
  • [38] Effect of long-term vigabatrin administration on the immature rat brain
    Qiao, M
    Malisza, KL
    Del Bigio, MR
    Kozlowski, P
    Seshia, SS
    Tuor, UI
    EPILEPSIA, 2000, 41 (06) : 655 - 665
  • [39] EFFECT OF LONG-TERM ETHANOL ADMINISTRATION ON BRAIN DENDRITES IN RAT
    VOZEH, F
    ZALUD, V
    ACTIVITAS NERVOSA SUPERIOR, 1990, 32 (03): : 196 - 197
  • [40] Effect of long-term administration of valproate on tryptophan, kynurenine and kynurenic acid content in rat brain cortex
    Fonderska, Paulina
    Pyzio, Lukasz
    Zakrocka, Izabela
    Turski, Waldemar A.
    Kocki, Tomasz
    PHARMACOLOGICAL REPORTS, 2015, 67 : 22 - 22
12345