Possible andrologic markers in elevated neonatal 17-hydroxyprogesterone

被引:1
|
作者
Cavarzere, Paolo [1 ]
Vincenzi, Monica [1 ]
Gaudino, Rossella [1 ]
Franceschi, Roberto [1 ]
Perlini, Silvia [1 ]
Camilot, Marta [1 ]
Teofoli, Francesca [1 ]
Antoniazzi, Franco [1 ]
Tato, Luciano [1 ]
机构
[1] Univ Verona, Pediat Clin, Dept Mother & Child, I-37134 Verona, Italy
关键词
Inhibin B; 17OH-P; newborn; weight; male; ADRENAL REST TUMORS; INHIBIN-B LEVELS; 21-HYDROXYLASE DEFICIENCY; GONADAL-FUNCTION; HIGH PREVALENCE; ADULT MALES; BOYS; GONADOTROPIN; CHILDHOOD; HORMONE;
D O I
10.1016/j.fertnstert.2010.04.040
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
In this prospective study, we analyzed 30 male infants with increased neonatal 17-hydroxyprogesterone (17OH-P) (patients) and for comparison 52 age-matched healthy babies (control subjects) with the aim of investigating the hypothalamic-pituitary-testis axis in the first 6 months of life. Although T, FSH, and LH levels were not significantly different in patients and control subjects, inhibin B was higher in patients than in control subjects. Therefore we suggest a clinical follow-up of these babies during childhood and puberty to verify the evolution of their condition. (Fertil Steril (R) 2010;94:2350-2. (C) 2010 by American Society for Reproductive Medicine.)
引用
收藏
页码:2350 / 2352
页数:3
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