Salmonella enterica Serotype Typhi with Nonclassical Quinolone Resistance Phenotype

被引：0

作者：

Accou-Demartin, Marie

Gaborieau, Valerie ^{[2
]}

Song, Yajun ^{[3
]}

Roumagnac, Philippe ^{[4
]}

Marchou, Bruno ^{[2
]}

Achtman, Mark ^{[3
]}

Weill, Francois-Xavier ^{[1
]}

机构：

[1] Inst Pasteur, Ctr Natl Reference Salmonella, Unite Bacteries Pathogenes Enter, F-75724 Paris 15, France

[2] Hop Purpan, Toulouse, France

[3] Univ Coll Cork, Cork, Ireland

[4] Ctr Cooperat Int Rech Agron Dev, Montpellier, France

来源：

EMERGING INFECTIOUS DISEASES | 2011年 / 17卷 / 06期

关键词：

FLUOROQUINOLONE BREAKPOINTS; CLINICAL-RESPONSE; UNITED-STATES; FEVER; INFECTION;

D O I：

10.3201/eid1706.101242

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure.

引用

页码：1091 / 1094

页数：4

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