Salmonella enterica Serotype Typhi with Nonclassical Quinolone Resistance Phenotype

被引：0
|
作者：
Accou-Demartin, Marie
Gaborieau, Valerie [2 ]
Song, Yajun [3 ]
Roumagnac, Philippe [4 ]
Marchou, Bruno [2 ]
Achtman, Mark [3 ]
Weill, Francois-Xavier [1 ]
机构：
[1] Inst Pasteur, Ctr Natl Reference Salmonella, Unite Bacteries Pathogenes Enter, F-75724 Paris 15, France
[2] Hop Purpan, Toulouse, France
[3] Univ Coll Cork, Cork, Ireland
[4] Ctr Cooperat Int Rech Agron Dev, Montpellier, France
来源：
EMERGING INFECTIOUS DISEASES | 2011年 / 17卷 / 06期
关键词：
FLUOROQUINOLONE BREAKPOINTS; CLINICAL-RESPONSE; UNITED-STATES; FEVER; INFECTION;
D O I：
10.3201/eid1706.101242
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure.
引用
收藏
页码：1091 / 1094
页数：4
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