Validity of the Quantitative EEG Statistical Pattern Recognition Method in Diagnosing Alzheimer's Disease

被引：22

作者：

Ommundsen, Nina ^{[1
]}

Engedal, Knut ^{[1
,2
]}

Oksengard, Anne Rita ^{[1
,3
,4
,5
]}

机构：

[1] Ullevaal Univ Hosp, Dept Geriatr Med, NO-0424 Oslo, Norway

[2] Ullevaal Univ Hosp, Norwegian Ctr Ageing & Hlth Res Educ & Serv Dev, NO-0424 Oslo, Norway

[3] Memory Clin, Dept Geriatr, Asker, Norway

[4] Baerum Hosp, Rud, Norway

[5] Karolinska Inst, NVS Dept, Sect Clin Geriatr, Karolinska Univ Hosp, Stockholm, Sweden

来源：

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS | 2011年 / 31卷 / 03期

关键词：

Alzheimer's disease; Dementia; Diagnostics; Electroencephalography; Mild cognitive impairment; Validate; MILD COGNITIVE IMPAIRMENT; RESTING EEG; DEMENTIA; POPULATION; ACCURACY;

D O I：

10.1159/000324878

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Aims: To evaluate the use of quantitative EEG (qEEG) statistical pattern recognition in diagnosing Alzheimer's disease (AD). Methods: qEEG was performed on 104 patients referred to a memory clinic. The qEEG results were compared to the clinical diagnosis made without access to the EEG results. Results: Of 30 patients with a clinical diagnosis of AD, 22 were test positive. Of the 74 patients without AD, 34 were test negative. The qEEG result was found to correlate with atrophy of the medial temporal lobe demonstrated on cerebral MRI (p = 0.002) and with scores on neuropsychological tests. Conclusion: The qEEG was poor at diagnosing AD, as it produced many false-positive results. Copyright (C) 2011 S. Karger AG, Basel

引用

页码：195 / 201

页数：7

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