Beyond Tsg101: the role of Alix in 'ESCRTing' HIV-1

被引：137
|
作者：
Fujii, Ken
Hurley, James H.
Freed, Eric O. [1 ]
机构：
[1] NCI, HIV Drug Resistance Program, Virus Cell Interact Sect, Frederick, MD 21702 USA
[2] NIH, Natl Inst Diabet & Digest & Kidney Dis, Mol Biol Lab, Bethesda, MD 20892 USA
来源：
NATURE REVIEWS MICROBIOLOGY | 2007年 / 5卷 / 12期
关键词：
D O I：
10.1038/nrmicro1790
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The limited coding capacity of retroviral genomes forces these viruses to rely heavily on the host-cell machinery for their replication. This phenomenon is particularly well illustrated by the interaction between retroviruses and components of the endosomal budding machinery that occurs during virus release. Here, we focus on the use of host-cell factors during HIV-1 budding and highlight recent progress in our understanding of the role of one such factor, Alix, in both viral and cellular membrane budding and fission events.
引用
收藏
页码：912 / 916
页数：5
相关论文
共 50 条
  • [31] A role of tumor susceptibility gene 101 (TSG101) in innate immune response of crayfish Procambarus clarkii
    Sun, Yu-Xuan
    Tang, Lin
    Gao, Jin
    Feng, Yuan-Yuan
    Peng, Tao
    Yu, Ying-Ying
    Yang, Liang-Li
    Sun, Yu
    Zhu, Bao-Jian
    DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2017, 76 : 268 - 273
  • [32] Tsg101 and Alix interact with murine leukemia virus Gag and cooperate with Nedd4 ubiquitin ligases during budding
    Segura-Morales, C
    Pescia, C
    Chatellard-Causse, C
    Sadoul, R
    Bertrand, E
    Basyuk, E
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (29) : 27004 - 27012
  • [33] Tsg101 regulates P1(4,5)P2/Ca2+ signaling for HIV-1 Gag assembly
    Ehrlich, Lorna S.
    Medina, Gisselle N.
    Photiadis, Sara
    Whittredge, Paul B.
    Watanabe, Susan
    Taraska, Justin W.
    Carter, Carol A.
    FRONTIERS IN MICROBIOLOGY, 2014, 5
  • [34] How HIV-1 hijacks ALIX
    Gottlinger, Heinrich
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2007, 14 (04) : 254 - 256
  • [35] How HIV-1 hijacks ALIX
    Heinrich G Göttlinger
    Nature Structural & Molecular Biology, 2007, 14 : 254 - 256
  • [36] Elucidation of New Binding Interactions with the Human Tsg101 Protein Using Modified HIV-1 Gag-p6 Derived Peptide Ligands
    Kim, Sung-Eun
    Liu, Fa
    Im, Young Jun
    Stephen, Andrew G.
    Fivash, Matthew J.
    Waheed, Abdul A.
    Freed, Eric O.
    Fisher, Robert J.
    Hurley, James H.
    Burke, Terrence R.
    ACS MEDICINAL CHEMISTRY LETTERS, 2011, 2 (05): : 337 - 341
  • [37] Analysis of the function of Tsg101 and AP-3 Delta-Adaptin in the trafficking of HIV-1 to the dendritic cell - T cell infectious synapse
    Nikolic, S.
    Blot, G.
    Garcia, E.
    Piguet, V.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2007, 127 : S75 - S75
  • [38] Role of the TSG101 gene in Epstein-Barr virus late gene transcription
    Chua, Huey-Huey
    Lee, Heng-Huan
    Chang, Shih-Shin
    Lu, Chih-Chung
    Yeh, Te-Huei
    Hsu, Tsuey-Ying
    Cheng, Tzu-Hao
    Cheng, Jiin-Tsuey
    Chen, Mei-Ru
    Tsai, Ching-Hwa
    JOURNAL OF VIROLOGY, 2007, 81 (05) : 2459 - 2471
  • [39] Recruitment of Tom1L1/Srcasm to Endosomes and the Midbody by Tsg101
    Yanagida-Ishizaki, Yuko
    Takei, Tomomi
    Ishizaki, Ray
    Imakagura, Hitoshi
    Takahashi, Senye
    Shin, Hye-Won
    Katoh, Yohei
    Nakayama, Kazuhisa
    CELL STRUCTURE AND FUNCTION, 2008, 33 (01) : 91 - 100
  • [40] Role of UEV-1A, a homologue of the tumor suppressor protein TSG101, in protection from DNA damage
    Thomson, TM
    Khalid, H
    Lozano, JJ
    Sancho, E
    Ariño, J
    FEBS LETTERS, 1998, 423 (01) : 49 - 52
12345