AN EFFICIENT FOUR-COMPONENT SYNTHESIS OF MULTISUBSTITUTED PYRANO[2,3-c]PYRAZOLE

被引：11
|
作者：
Ablajan, Keyume [1 ]
Maimaiti, Zulipiya [1 ]
机构：
[1] Xinjiang Univ, Coll Chem & Chem Engn, Urumqi 830046, Peoples R China
来源：
SYNTHETIC COMMUNICATIONS | 2012年 / 42卷 / 13期
关键词：
Aldehyde; malononitrile; methyl methyl-3-oxovalerate; multicomponent reaction; one-pot synthesis; pyrano[2,3-c]pyrazole; ONE-POT SYNTHESIS; CARBONYL-COMPOUNDS; CYANOACETIC ACID; SOLVENT-FREE; DERIVATIVES; APOPTOSIS;
D O I：
10.1080/00397911.2010.551169
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of substituted pyrano[2,3-c]pyrazole derivatives were synthesized by a one-pot reaction of methyl 4-methyl-3-oxovalerate, phenylhydrazine, aromatic aldehyde, and malononitrile in ethanol with catalysis by triethylamine. The title compounds were obtained in good to excellent yields. A possible mechanism for this reaction was proposed.
引用
收藏
页码：1959 / 1966
页数：8
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