AN EFFICIENT FOUR-COMPONENT SYNTHESIS OF MULTISUBSTITUTED PYRANO[2,3-c]PYRAZOLE

被引：11

作者：

Ablajan, Keyume ^{[1
]}

Maimaiti, Zulipiya ^{[1
]}

机构：

[1] Xinjiang Univ, Coll Chem & Chem Engn, Urumqi 830046, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2012年 / 42卷 / 13期

关键词：

Aldehyde; malononitrile; methyl methyl-3-oxovalerate; multicomponent reaction; one-pot synthesis; pyrano[2,3-c]pyrazole; ONE-POT SYNTHESIS; CARBONYL-COMPOUNDS; CYANOACETIC ACID; SOLVENT-FREE; DERIVATIVES; APOPTOSIS;

D O I：

10.1080/00397911.2010.551169

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of substituted pyrano[2,3-c]pyrazole derivatives were synthesized by a one-pot reaction of methyl 4-methyl-3-oxovalerate, phenylhydrazine, aromatic aldehyde, and malononitrile in ethanol with catalysis by triethylamine. The title compounds were obtained in good to excellent yields. A possible mechanism for this reaction was proposed.

引用

页码：1959 / 1966

页数：8

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