Scaleable synthesis of a GPR40 agonist

被引：0
|
作者：
Fenster, Michael D. B. [1 ]
Ronald, Hanson L. [1 ]
Katipally, Kishta [1 ]
Paul, Tapas [2 ]
Rao, Ramana [2 ]
Simmons, Eric M. [1 ]
Young, Ian S. [1 ]
Zhu, Jason J. [1 ]
机构：
[1] Bristol Myers Squibb Co, Dept Chem Dev, New Brunswick, NJ 08903 USA
[2] Syngene Int Ltd, Bangalore, Karnataka, India
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2014年 / 248卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
119-ORGN
引用
收藏
页数：1
相关论文
共 50 条
  • [31] Stimulating Beta Cell Replication and Improves Islet Graft Function by a GPR40 and GPR120 Dual Agonist
    Gao, Jie
    Weng, Guobin
    O'Brien, Timothy D.
    Ansarullah
    Lu, Yan
    Koenig, Mar-Tha
    Deruyter, Brittany
    Guo, Zhiguang
    DIABETES, 2012, 61 : A73 - A73
  • [32] Stimulating Beta Cell Replication and Improving Islet Graft Function by a GPR40 and GPR120 Dual Agonist
    Gao, J.
    Weng, G.
    Aasarullah, A.
    Lu, Y.
    Holstein, M.
    Deruyter, B.
    O'Brien, T. D.
    Guo, Z.
    TRANSPLANTATION, 2012, 94 (10) : 567 - 567
  • [33] Molecular docking and molecular dynamics simulation studies of GPR40 receptor-agonist interactions
    Lu, Shao-Yong
    Jiang, Yong-Jun
    Lv, Jing
    Wu, Tian-Xing
    Yu, Qing-Sen
    Zhu, Wei-Liang
    JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2010, 28 (08): : 766 - 774
  • [34] Discovery and development of CPL207280 as new GPR40/FFA1 agonist
    Mach, Mateusz
    Bazydlo-Guzenda, Katarzyna
    Buda, Pawel
    Matloka, Mikolaj
    Dzida, Radoslaw
    Stelmach, Filip
    Galazka, Kinga
    Wasinska-Kalwa, Malgorzata
    Smuga, Damian
    Holowinska, Dagmara
    Dawid, Urszula
    Gurba-Bryskiewicz, Lidia
    Wisniewski, Krzysztof
    Dubiel, Krzysztof
    Pieczykolan, Jerzy
    Wieczorek, Maciej
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 226
  • [35] Discovery of ID11014A as a Novel GPR40 Agonist for the Treatment of Type 2 Diabetes
    An, Kyungmi
    Hong, Changhee
    Cui, Shuolin
    Kwak, Hyunjung
    Song, Hyojung
    Park, Joontae
    Moon, Anna
    Kim, Jeongah
    Yang, Jihun
    Lee, Jungwoo
    Yoon, Jongmin
    Lee, Myongjae
    Jeong, Donggu
    Kim, Dohee
    Lee, Dongil
    Koh, Eunji
    Shin, Jeongcheol
    Hong, Dahae
    Park, Jun-Gu
    Je, In-Gyu
    Lee, Seolhee
    Lee, Hongsub
    Park, Soobong
    Kang, Jaehoon
    DIABETES, 2017, 66 : LB40 - LB40
  • [36] GPR40 agonist, an emerging antidiabetic agent, regulates foam cell formation and endothelial cytotoxicity
    Hwang, H. -J.
    Kim, J.
    Yun, S.
    Park, M.
    Song, E.
    Jang, S.
    Jang, A.
    Choi, K.
    Baik, S.
    Yoo, H.
    DIABETOLOGIA, 2023, 66 (SUPPL 1) : S483 - S483
  • [37] Modulation of insulin secretion by GPR40 agonism
    Herling, A.
    Defossa, E.
    Haschke, G.
    Dietrich, V
    Stengelin, S.
    Keil, S.
    Dudda, A.
    Wagner, M.
    Ruus, P.
    Kramer, W.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2011, 383 : 6 - 6
  • [38] Targeting GPR40 for diabetes: A multipronged approach
    Johnston, Jennifer
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 255
  • [39] GPR40 (FFAR1) Modulators
    Medina, Julio C.
    Houze, Jonathan B.
    ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 43, 2008, 43 : 75 - +
  • [40] Role of GPR40 in Intestinal Hormone Secretion
    Ross, Sean
    Nystrom, Christopher
    Mcnulty, Judi
    Anderson, Donald
    Croom, Dallas
    Chen, Lihong
    Liu, Yaping
    DIABETES, 2011, 60 : A128 - A128
12345