共 50 条
- [21] Discovery of TAK-875: A potent, selective, and orally bioavailable GPR40 agonistABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 240Negoro, NobuyukiSasaki, ShinobuMikami, SatoshiIto, MasahiroSuzuki, MasamiTsujihata, YoshiyukiIto, RyoHarada, AyakoTakeuchi, KojiSuzuki, NobuhiroMiyazaki, JunichiSantou, TakashiKanzaki, NaoyukiSatou, ShinichiOdani, TomoyukiSakamoto, JunichiFunami, MiyukiTanaka, ToshimasaKogame, AkifumiMatsunaga, ShinichiroYasuma, TsuneoMomose, Yu
- [22] Discovery of TAK-875: A Potent, Selective, and Orally Bioavailable GPR40 AgonistACS MEDICINAL CHEMISTRY LETTERS, 2010, 1 (06): : 290 - 294Negoro, NobuyukiSasaki, ShinobuMikami, SatoshiIto, MasahiroSuzuki, MasamiTsujihata, YoshiyukiIto, RyoHarada, AyakoTakeuchi, KojiSuzuki, NobuhiroMiyazaki, JunichiSantou, TakashiOdani, TomoyukiKanzaki, NaoyukiFunami, MiyukiTanaka, ToshimasaKogame, AkifumiMatsunaga, ShinichiroYasuma, TsuneoMomose, Yu
- [23] Bidirectional, iterative approach to the structural delineation of the functional "Chemoprint" in GPR40 for agonist recognitionJOURNAL OF MEDICINAL CHEMISTRY, 2007, 50 (13) : 2981 - 2989Tikhonova, Irina G.Sum, Chi ShingNeumann, SusanneThomas, Craig J.Raaka, Bruce M.Costanzi, StefanoGershengorn, Marvin C.
- [24] Discovery of AM-1638: A potent and orally bioavailable GPR40 full agonistABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244Brown, Sean P.Dransfield, Paul J.Houze, Jonathan B.Vimolratana, MarcPattaropong, VateeZhu, LiushengMedina, Julio C.Wong, SimonSwaminath, GayathriLin, DanZhang, JaneZhuang, RunGuo, Qi
- [25] Asymmetric syntheses of a GPR40 receptor agonist via diastereoselective and enantioselective conjugate alkynylationTETRAHEDRON, 2010, 66 (26) : 4730 - 4737Woo, Jacqueline C. S.Cui, ShengWalker, Shawn D.Faul, Margaret M.
- [26] Preclinical efficacy of the novel GPR40 agonist CPL207-280 in neuropathyDIABETOLOGIA, 2023, 66 (SUPPL 1) : S107 - S107Jaworski, T.Janiszewski, M.Buda, P.Vialichka, V.Bazydlo-Guzenda, K.Mach, M.Galazka, K.Dominowski, J.Gorka, M.Salat, K.Popik, P.Dubiel, K.Pieczykolan, J.Wieczorek, M.
- [27] TAK-875 Is a Partial Agonist of the Free Fatty Acid Receptor GPR40DIABETES, 2013, 62 : A582 - A582Mancini, ArturoCarpentier, EricBouvier, MichelPoitout, Vincent
- [28] Vincamine as a GPR40 agonist improves glucose homeostasis in type 2 diabetic miceJOURNAL OF ENDOCRINOLOGY, 2019, 240 (02) : 195 - 214Du, TeYang, LiuXu, XuShi, XiaofanXu, XinLu, JianLv, JianluHuang, XiChen, JingWang, HeyaoYe, JimingHu, LihongShen, Xu
- [29] Synthesis of the GPR40 Partial Agonist MK-8666 through a Kinetically Controlled Dynamic Enzymatic Ketone ReductionORGANIC LETTERS, 2016, 18 (22) : 5888 - 5891Hyde, Alan M.Liu, ZhijianKosjek, BirgitTan, LushiKlapars, ArtisAshley, Eric ItZhong, Yong-LiAlvizo, OscarAgard, Nicholas J.Liu, GuiquanGu, XiuyanYasuda, NobuyoshiLimanto, JohnHuffman, Mark K.Tschaen, David M.
- [30] Design, synthesis and biological evaluation of indane derived GPR40 agoPAMsBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 29 (14) : 1842 - 1848Pio, BarbaraChobanian, Harry R.Guo, YanJosien, HubertHagmann, William K.Miller, MichaelTrujillo, Maria E.Kirkland, MelissaKosinski, DanielMane, JoelPachanski, MicheleCheewatrakoolpong, BoonlertAshley, EricOrr, RobertWright, Michael J.Bugianesi, RandalSouza, SarahZhang, XiaopingDi Salvo, JerryWeinglass, Adam B.Tschirret-Guth, RichardSamuel, KopparaChen, QingShang, JackieLamca, JamesEhrhart, JuliannNargund, RaviHoward, Andrew D.Colletti, Steven L.