Metal-free cascade cyclization of alkenes toward perfluorinated oxindoles

被引：42
|
作者：
Tang, Shi [1 ,3 ]
Li, Zhi-Hao [1 ]
Wang, Ming-Wei [1 ]
Li, Zhi-Ping [1 ]
Sheng, Rui-Long [2 ]
机构：
[1] Jishou Univ, Coll Chem & Chem Engn, Jishou 416000, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China
[3] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2015年 / 13卷 / 18期
基金：
中国博士后科学基金; 中国国家自然科学基金;
关键词：
COPPER-CATALYZED TRIFLUOROMETHYLATION; N-ARYLACRYLAMIDES; RADICAL-ADDITION; CF3-CONTAINING OXINDOLES; ACTIVATED ALKENES; BOND FORMATION; PERFLUOROALKYLATION; IODIDES; FLUOROALKYLATION; CONSTRUCTION;
D O I：
10.1039/c5ob00454c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple AIBN-mediated cyclization reaction of activated alkenes toward perfluorinated oxindoles is developed. In the presence of readily available AIBN, N-arylacrylamide and perfluoroalkyl iodides underwent perfluorination reaction to give perfluorinated oxindoles in good to excellent yields under metal-free conditions.
引用
收藏
页码：5285 / 5288
页数：4
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