Metal-free cascade cyclization of alkenes toward perfluorinated oxindoles

被引：42

作者：

Tang, Shi ^{[1
,3
]}

Li, Zhi-Hao ^{[1
]}

Wang, Ming-Wei ^{[1
]}

Li, Zhi-Ping ^{[1
]}

Sheng, Rui-Long ^{[2
]}

机构：

[1] Jishou Univ, Coll Chem & Chem Engn, Jishou 416000, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China

[3] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2015年 / 13卷 / 18期

基金：

中国博士后科学基金; 中国国家自然科学基金;

关键词：

COPPER-CATALYZED TRIFLUOROMETHYLATION; N-ARYLACRYLAMIDES; RADICAL-ADDITION; CF3-CONTAINING OXINDOLES; ACTIVATED ALKENES; BOND FORMATION; PERFLUOROALKYLATION; IODIDES; FLUOROALKYLATION; CONSTRUCTION;

D O I：

10.1039/c5ob00454c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple AIBN-mediated cyclization reaction of activated alkenes toward perfluorinated oxindoles is developed. In the presence of readily available AIBN, N-arylacrylamide and perfluoroalkyl iodides underwent perfluorination reaction to give perfluorinated oxindoles in good to excellent yields under metal-free conditions.

引用

页码：5285 / 5288

页数：4

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