Palladium-catalyzed cyanation reactions of thiophene halides

被引：12
|
作者：
Erker, T [1 ]
Nemec, S [1 ]
机构：
[1] Univ Vienna, Inst Pharmaceut Chem, A-1090 Vienna, Austria
来源：
SYNTHESIS-STUTTGART | 2004年 / 01期
关键词：
nitriles; thiophene; palladium; catalysis; cyanation;
D O I：
10.1055/s-2003-42490
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The described method provides an efficient cyanation reaction of thiophene halides using tris(dibenzylidene-acetone)dipalladium(0), 1,1'-bis-(diphenylphosphino)ferrocene) and zinc powder as the catalyst system and Zn(CN)(2) as the cyanide source. Several thiophenes with various substituents are effectively cyanated under these conditions.
引用
收藏
页码：23 / 25
页数：3
相关论文
共 50 条
  • [21] Potassium hexacyanoferrate(II) - a new cyanating agent for the palladium-catalyzed cyanation of aryl halides
    Schareina, T
    Zapf, A
    Beller, M
    CHEMICAL COMMUNICATIONS, 2004, (12) : 1388 - 1389
  • [22] Synthesis of thiophene derivatives via palladium-catalyzed coupling reactions
    Arai, Nobumichi
    Miyaoku, Takayuki
    Teruya, Shota
    Mori, Atsunori
    TETRAHEDRON LETTERS, 2008, 49 (06) : 1000 - 1003
  • [23] Palladium-catalyzed reactions of hexaethyldigermane with 2-alkenyl halides
    Nakano, T
    Yamashita, H
    Enokido, T
    Ono, K
    Migita, T
    MAIN GROUP CHEMISTRY, 1996, 1 (02) : 179 - 181
  • [24] PALLADIUM-CATALYZED REACTIONS OF VINYLIC HALIDES WITH ALLYLIC ALCOHOLS AND AMINES
    HECK, RF
    KAO, LC
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1981, 181 (MAR): : 48 - PETR
  • [25] Progress in the palladium-catalyzed cyanation of aryl chlorides
    Sundermeier, M
    Zapf, A
    Mutyala, S
    Baumann, W
    Sans, J
    Weiss, S
    Beller, M
    CHEMISTRY-A EUROPEAN JOURNAL, 2003, 9 (08) : 1828 - 1836
  • [26] Palladium-Catalyzed Carbonylation Reactions of Aryl Halides and Related Compounds
    Brennfuehrer, Anne
    Neumann, Helfried
    Beller, Matthias
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (23) : 4114 - 4133
  • [27] Palladium-Catalyzed Cyanation of Aryl Sulfonium Salts
    Liu, Mengna
    Cui, Benqiang
    Zhong, Chuntao
    Shi, Yanhui
    Dang, Yanfeng
    Cao, Changsheng
    ORGANIC LETTERS, 2023, 25 (22) : 3989 - 3994
  • [28] Palladium-Catalyzed Cyanation of Aryl Halides Using Formamide and Cyanuric Chloride as a New "CN" Source
    Niknam, Esmaeil
    Panahi, Farhad
    Khalafi-Nezhad, Ali
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2020, 2020 (18) : 2699 - 2707
  • [29] Palladium-Catalyzed Reactions
    Della Ca, Nicola
    CATALYSTS, 2021, 11 (05)
  • [30] The development of efficient catalysts for palladium-catalyzed coupling reactions of aryl halides
    Zapf, A
    Beller, M
    CHEMICAL COMMUNICATIONS, 2005, (04) : 431 - 440
12345