Palladium-catalyzed cyanation reactions of thiophene halides

被引：12
|
作者：
Erker, T [1 ]
Nemec, S [1 ]
机构：
[1] Univ Vienna, Inst Pharmaceut Chem, A-1090 Vienna, Austria
来源：
SYNTHESIS-STUTTGART | 2004年 / 01期
关键词：
nitriles; thiophene; palladium; catalysis; cyanation;
D O I：
10.1055/s-2003-42490
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The described method provides an efficient cyanation reaction of thiophene halides using tris(dibenzylidene-acetone)dipalladium(0), 1,1'-bis-(diphenylphosphino)ferrocene) and zinc powder as the catalyst system and Zn(CN)(2) as the cyanide source. Several thiophenes with various substituents are effectively cyanated under these conditions.
引用
收藏
页码：23 / 25
页数：3
相关论文
共 50 条
  • [11] Mild Palladium-Catalyzed Cyanation of (Hetero)aryl Halides and Triflates in Aqueous Media
    Cohen, Daniel T.
    Buchwald, Stephen L.
    ORGANIC LETTERS, 2015, 17 (02) : 202 - 205
  • [12] Mild palladium-catalyzed cyanation of (hetero)aryl halides and triflates in aqueous media
    Cohen, Daniel
    Buchwald, Stephen
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 250
  • [13] A convenient and efficient procedure for the palladium-catalyzed cyanation of aryl halides using trimethylsilylcyanide
    Sundermeier, M
    Mutyala, S
    Zapf, A
    Spannenberg, A
    Beller, M
    JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2003, 684 (1-2) : 50 - 55
  • [14] Ethyl Cyanoacetate: A New Cyanating Agent for the Palladium-Catalyzed Cyanation of Aryl Halides
    Zheng, Shuyan
    Yu, Chunhui
    Shen, Zhengwu
    ORGANIC LETTERS, 2012, 14 (14) : 3644 - 3647
  • [15] Palladium-catalyzed cyanation of aryl perfluorooctylsulfonates
    Zhu, Yi-Zhong
    Cai, Chun
    AUSTRALIAN JOURNAL OF CHEMISTRY, 2008, 61 (08) : 581 - 584
  • [16] Palladium-catalyzed cyanation of aryl triflates
    Zhu, Yi-Zhong
    Cai, Chun
    SYNTHETIC COMMUNICATIONS, 2008, 38 (16) : 2753 - 2760
  • [17] Palladium-catalyzed reactions of acylzirconocene chloride with organic halides
    Hanzawa, Y
    Tabuchi, N
    Taguchi, T
    TETRAHEDRON LETTERS, 1998, 39 (34) : 6249 - 6252
  • [18] Palladium-catalyzed coupling reactions of paramagnetic vinyl halides
    Kálai, T
    Balog, M
    Jekö, J
    Hubbell, WL
    Hideg, K
    SYNTHESIS-STUTTGART, 2002, (16): : 2365 - 2372
  • [19] Palladium-Catalyzed Catellani Aminocyclopropanation Reactions with Vinyl Halides
    Khanna, Avinash
    Premachandra, Ilandari Dewage Udara Anulal
    Sung, Paul D.
    Van Vranken, David L.
    ORGANIC LETTERS, 2013, 15 (12) : 3158 - 3161
  • [20] Palladium-catalyzed coupling reactions of paramagnetic vinyl halides
    Kálai, Tamás
    Balog, Mária
    Jeko, József
    Hubbell, Wayne L.
    Hideg, Kálmán
    Synthesis, 2002, (16) : 2365 - 2372
12345