Facile synthesis of a phosphotriester intermediates for solution-phase preparation of oligonucleotide phosphorothioates

被引：0
|
作者：
Miyashita, T
Mori, K
Shinozuka, K
机构：
[1] Yamasa Corp, Div Biochem, Chiba 2880056, Japan
[2] Gunma Univ, Fac Engn, Dept Chem, Gunma 3760052, Japan
来源：
CHEMISTRY LETTERS | 1999年 / 01期
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Fully protected 2'-deoxynucleoside phosphorothioate triester derivatives, which are key starting materials for the large-scale solution-phase preparation of phosphorothioate oligonucleotides, were easily synthesized by a new method starting from common, fully protected 2'-deoxynucleosides.
引用
收藏
页码：39 / 40
页数：2
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